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005 | 20250223030813.0 | ||
008 | 130327s2011 ua dh f m 000 0 eng d | ||
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_aEG-GiCUC _beng _cEG-GiCUC |
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041 | 0 | _aeng | |
049 | _aGift | ||
097 | _aM.Sc | ||
099 | _aCai01.34.M.Sc.2011.Mo.M | ||
100 | 0 | _aMohammed Weam Ahmed | |
245 | 1 | 0 |
_aModulating the balance between COX2 and PDE5 inhibitory activities of celecoxib analogues by adapting the nature of the core ring and peripheral rings substitution / _cMohammed Weam Ahmed ; Supervised Ashraf H. Abadi , Raimund Niess |
246 | 1 | 5 | _aتحوير التوازن التثبيطى لعقار السيليكوكسيب لانزيمى الكوكس - 2 والفو سفودايستراز - 5 عن طريق تكييف طبيعة الحلقة الأساسية ومستبدلات الحلقات الطرفية |
260 |
_aCairo : _bMohammed Weam Ahmed , _c2011 |
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_a71Leaves : _bcharts , facsimiles ; _c30cm |
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502 | _aThesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry | ||
520 | _aThe identification and characterization of inducible form of cyclooxygenase (COX2) in inflammatory cells in the early 1990s were the start of a race to the development of more selective nonsteroidal anti - inflammatory drugs (NSAIDs) , collectively known as coxibs , with reduced gastric - and nephrotoxicity compared to classical NSAIDs . However , coxibs were reported to increase the incidence of systemic hypertension and thromboembolic complications including myocardial infarction | ||
700 | 0 |
_aAshraf Mostafa Abadi , _eSupervisor |
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700 | 0 |
_aRaimund Niess , _eSupervisor |
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856 | _uhttp://172.23.153.220/th.pdf | ||
905 |
_aFatma _eCataloger |
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905 |
_aNazla _eRevisor |
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_2ddc _cTH |
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_c42276 _d42276 |