000 01586cam a2200277 a 4500
003 EG-GiCUC
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008 130401s2010 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aGift
097 _aM.Sc
099 _aCai01.34.M.Sc.2010.Am.S
100 0 _aAmal Mahmoud Yassin Mohsen
245 1 0 _aSynthesis and pharmacological evaluation of 1-Benzyl and 1-Benzoyl melatonin analogs as ligands for melatonin receptors /
_cAmal Mahmoud Yassin Mohsen ; Supervised Darius P. Zlotos
246 1 5 _aتشييد وتقييم بيولوجى ل ن 1 بنزايل و ن 1 بنزويل من مشتقات الميلاتونين كلجائن لمستقبلات الميلاتونين
260 _aCairo :
_bAmal Mahmoud Yassin Mohsen ,
_c2010
300 _a84Leaves :
_bcharts , facsimiles ;
_c30cm
502 _aThesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
520 _aThe neurohormone melatonin (MLT) exerts its diverse physiological actions mostly through activation of the two G-protein-coupled MT₁ and MT₂ receptors . An accurate characterization of MLT receptor-mediated functions requires MT₁ and MT₂ selective ligands . One of the most selective MT₂ antagonists up to date is the p - chlorobenzl substituted indole derivative UCM 454
700 0 _aDarius Pawel Zlotos ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aFatma
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c42379
_d42379