000 01461cam a2200277 a 4500
003 EG-GiCUC
005 20250223030818.0
008 130403s2011 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aGift
097 _aM.Sc
099 _aCai01.34.M.Sc.2011.Sh.D
100 0 _aShreen Mohamad Elnashar
245 1 0 _aDesign and synthesis of novel tetrahydro Ý-carboline derivatives and their biological evaluation as phosphodiesterase 5 inhibitors and apoptotic agents /
_cShreen Mohamad Elnashar ; Supervised Ashraf H. Abadi , Nermin S. Ahmed
260 _aCairo :
_bShreen Mohamad Elnashar ,
_c2011
300 _a91 Leaves :
_bfacsimiles ;
_c30cm
502 _aThesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
520 _aRecently, many studies and researches are carried out to study PDE5 and its inhibitors due to their promising therapeutic uses. PDE5 has been successfully targeted for treatment of male erectile dysfunction. The success of sildenafil (Viagra®), vardenafil (Levitra®) and tadalafil (Cialis®) in this regard has renewed interest in PDE5 as potential pharmacological targets
700 0 _aAshraf H. Abadi ,
_eSupervisor
700 0 _aNermin S. Ahmed ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c42442
_d42442