000 01734cam a2200349 a 4500
003 EG-GiCUC
005 20250223030849.0
008 130917s2013 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.08.08.Ph.D.2013.Ib.P
100 0 _aIbtehal Salah Addin Abdulsaboor Ahmad
245 1 2 _aA pharmaceutical study on zaleplon /
_cIbtehal Salah Addin Abdulsaboor Ahmad ; Supervised Ahmed Abdelbary , Omaima N. Elgazayerly , Arwa Elhagrasy
246 1 5 _aدراسة صيدلية على عقار الزاليبلون
260 _aCairo :
_bIbtehal Salah Addin Abdulsaboor Ahmad ,
_c2013
300 _a238P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Pharmacy- Department of Pharmaceutics
520 _aZaleplon is a hypnotic drug used for the treatment of insomnia . It has elimination half life of 1 hour . But , it suffers from low bioavailability following oral administration using traditional dosage forms due its poor solubility and its extensive first pass metabolism . It needs to be incorporated into a dosage form that enhances its bioavailability and also be in a dosage form which sustains the release of the drug for duration of time enough to maintain sleep
530 _aIssued also as CD
653 4 _aMicroparticles
653 4 _aOrally disintegrating tablets
653 4 _aZaleplon
700 0 _aAhmed Abdelbary ,
_eSupervisor
700 0 _aArwa Elhagrasy ,
_eSupervisor
700 0 _aOmaima N. Elgazayerly ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aFatma
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c43536
_d43536