000 02085cam a2200349 a 4500
003 EG-GiCUC
005 20250223030914.0
008 131216s2013 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.07.M.Sc.2013.Ha.D
100 0 _aHanaa Almelhuda Abdelwajed
245 1 0 _aDetection of expansion of CD4⁺ CD28⁻ T cells in patients with rheumatoid arthritis by flow cytometry /
_cHanaa Almelhuda Abdelwajed ; Supervised Mervat Saad Elansary , Esmat Mohamed Elhusseiny , Nancy M. Elguindy
246 1 5 _a فى مرضى التهاب المفاصل الرثيانى باستخدام جهاز التدفق الخلوى (CD٤⁺ CD{u06F2}{u06F8}⁻) تحديد مدى انتشار الخلايا الليمفاوية التوتية فئة
260 _aCairo :
_bHanaa Almelhuda Abdelwajed ,
_c2013
300 _a116 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
520 _aClonal expansion of CD4⁺ CD28⁻ T cells is a characteristic finding in patients with rheumatoid arthritis CD4⁺CD28⁻ T cells are oligoclonal lymphocytes that are rare in healthy individuals, but are found in high percentage in patients with rheumatoid arthritis . The presence of significant numbers of CD4⁺ CD28⁻ T cells could shift the immune response from B-cells activation and production of immunoglobulins toward activation of type-1 T helper cells and production of IFN-y and involvement of macrophages releasing matrix - degrading proteases
530 _aIssued also as CD
653 4 _aCD4⁺ CD28⁻ T cells
653 4 _aFlow cytometry
653 4 _aRheumatoid arthritis
700 0 _aEsmat Mohamed Elhusseiny ,
_eSupervisor
700 0 _aMervat Saad Elansary ,
_eSupervisor
700 0 _aNancy M. Elguindy ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSoheir
_eCataloger
942 _2ddc
_cTH
999 _c44442
_d44442