000			02196cam a2200349 a 4500
003			EG-GiCUC
005			20250223031042.0
008			140917s2014 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.08.09.Ph.D.2014.Ma.N
100	0		_aMarwa Ashour Masoud
245	1	0	_aNeuropharmacological evaluation of the possible effects of certain psychotropic and hepatotropic drugs in hepatic encephalopathy induced in rats / _cMarwa Ashour Masoud ; Supervised Sanaa A. Kenawy , Hanaa A. Mansour , Rania M. Abdelsalam
246	1	5	_aتقييم فارماكولوجى عصبى للتأثيرات المحتملة لبعض الأدوية النفسية والأدوية المؤثرة فى الكبد فى إعتلال المخ الكبدى المحدث فى الجرذان
260			_aCairo : _bMarwa Ashour Masoud , _c2014
300			_a205 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology
520			_aThe present study aimed to investigate the possible protective effects of certain hepatotropic drugs (neomycin and lactulose) and certain psychotropic drugs (fluoxetine and donepezil) in thioacetamide (TAA)-induced hepatic encephalopathy (HE) in rats. TAA (200mg/kg, p.o) was administered daily for two successive days at 24 hr interval to induce HE. Neomycin (540 mg/kg, p.o), lactulose (8 ml/kg, p.o), fluoxetine (10 mg/kg, p.o) or donepezil (10 mg/kg, p.o) were administered daily for seven successive days starting five days before TAA administration. The TAA group showed lower motor activity than the normal group by using open field and forced swimming tests
530			_aIssued also as CD
653		4	_aHepatic encephalopathy
653		4	_aNeomycin
653		4	_aThioacetamide
700	0		_aHanaa Abdelfattah Mansour , _eSupervisor
700	0		_aRania Mohsen Abdelsalam , _eSupervisor
700	0		_aSanaa Abdelbaky Kenawy , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aAml _eCataloger
905			_aNazla _eRevisor
942			_2ddc _cTH
999			_c47402 _d47402