000 02145cam a2200349 a 4500
003 EG-GiCUC
005 20250223031059.0
008 141027s2014 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.32.Ph.D.2014.Ma.E
100 0 _aMarwa Salah Elsayed Shabana
245 1 0 _aEvaluation of the classical complement pathway in activation of rheumatoid arthritis /
_cMarwa Salah Elsayed Shabana ; Supervised Samia Mohamad Hassan Fadda , Azza Ahmed Aboulenein , Hanan Elsayed Ali Darweesh
246 1 5 _aتقييم المسار الكلاسيكى المتمم فى نشاط الروماتيود المفصلى
260 _aCairo :
_bMarwa Salah Elsayed Shabana ,
_c2014
300 _a136 Leaves :
_bcharts ;
_c30cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Rheumatology and Rehabilitation
520 _aComplement activation has been implicated in the pathogenesis of RA. C1q {u2013} C4 complexes are a specific parameter of classical pathway activation. We aimed to investigate plasma levels of complement parameter; C1q and activated C4 in rheumatoid arthritis, and also to assess their association with disease activity. 50 RA patients classified into inactive RA group whose DAS 28 < 2.6 (n = 23 / 50) and active group had DAS 28 {u2265} 2.6 (n = 27 / 50) and control group (n = 20). RA patients were submitted to full history taking, full clinical examination, routine laboratory investigations, assessment of disease activity. CIq antibodies and C4d antibodies were measured using enzyme - linked Immunosorbent assay (ELISA) technique
530 _aIssued also as CD
653 4 _aClassical complement pathway
653 4 _aDisease activity parameters
653 4 _aRheumatoid arthritis
700 0 _aAzza Ahmed Aboulenein ,
_eSupervisor
700 0 _aHanan Elsayed Ali Darweesh ,
_eSupervisor
700 0 _aSamia Mohamad Hassan Fadda ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c47976
_d47976