000 01990cam a2200337 a 4500
003 EG-GiCUC
005 20250223031101.0
008 141029s2013 ua o f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.09.04.M.Sc.2013.As.I
100 0 _aAsmaa Salem Shanab
245 1 0 _aImmunohistochemical expression of claudin 1 in oral squamous cell carcinoma /
_cAsmaa Salem Shanab ; Supervised Mohsen Kazem Abdellatif , Dina Soliman Khater
246 1 5 _aدراسة مناعية نسجية كيميائية للكشف عن كلودين ١ فى سرطان الخلايا الحرشفية فى الفم
260 _aCairo :
_bAsmaa Salem Shanab ,
_c2013
300 _a87 P. :
_bphotographs ;
_c30cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral Pathology
520 _aTight junctions (TJs) are the most apical intercellular junctions, play major play major roles in controlling apical / basolateral polarity and acting as paracellular barriers. Furthermore, they are also known to participate in the control of fproliferation and differentiation. It is now well - established that dys - regulation o these functions contributes to initiation and progression of cancer. It has become clear that the claudins, members of a large family of 27 closely related transmembrane proteins, play a crucial role in formation, integrity and function of TJs. Some authors investigated the expression of claudin - 1 (Cldn - 1) in different human cancers
530 _aIssued also as CD
653 4 _aClaudin - 1
653 4 _aImmunohistochemistry and Oral squamous cell carcinoma
653 4 _aTight junctions
700 0 _aDina Soliman Khater ,
_eSupervisor
700 0 _aMohsen Kazem Abdellatif ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c48028
_d48028