000 02657cam a2200337 a 4500
003 EG-GiCUC
005 20250223031106.0
008 141113s2013 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.09.04.M.Sc.2013.As.I
100 0 _aAsmaa Mohamed Abougabal
245 1 0 _aImmunohistochemical expression of vascular cell adhesion molecule-1 in salivary gland tumors /
_cAsmaa Mohamed Abougabal ; Supervised Amina Kamel Amin , Amal Hassan Abdelrahman
246 1 5 _aالتوزيع المناعى الهيستوكيميائى للجزئ رقم واحد للاصق الخلية الدموى فى أورام الغدد اللعابية
260 _aCairo :
_bAsmaa Mohamed Abougabal ,
_c2013
300 _a132 Leaves :
_bcharts , facsimiles ;
_c30cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral Pathology
520 _aBackground: In recent years, the involvement of adhesion molecules in tumor development and formation of metastatic foci has become an object of research. Scientists have been trying to determine the significance of their expression in early diagnosis, in the assessment of cancer stage and metastatic development. Their role in local tumor growth, in the formation of distant metastases and involvement in angiogenesis has been investigated. The study was conducted to investigate salivary gland tumors for the following: Immunohistochemical expression of VCAM-1 and the relationship between VCAM-1 as regard tumor malignancy grade, tumor angiogenesis and MVD. Materials and methods: Fourty eight paraffin blocks of salivary gland neoplasms (13 benign and 35 malignant), in addition to five specimens of normal minor salivary glands that served as a control, were immunohistochemically stained with VCAM-1 antibody. ANOVA and Tukey's tests were used for the statistical analysis, to compare between the control and the different types of benign and malignant salivary gland neoplasms. Results:VCAM-1 immunoreactivity has been detected in normal and tumor tissues. The reaction was observed in tumor cells as well as intratumoral and peritumoral ECs, especially in vessel abundant regions
530 _aIssued also as CD
653 4 _aClaudin 1
653 4 _aImmunohistochemistry and oral squamous
653 4 _aTight junctions
700 0 _aAmal Hassan Abdelrahman ,
_eSupervisor
700 0 _aAmina Kamel Amin ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAml
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c48205
_d48205