000 02307cam a2200325 a 4500
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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.03.M.Sc.2014.Az.E
100 0 _aAzza Abusree Ahmed Elsaid
245 1 0 _aEffect of bone marrow derived mesenchymal stem cell on indomethacin induced gastric injury in rats /
_cAzza Abusree Ahmed Elsaid ; Supervised Laila Ahmed Rashed , Doaa Mostafa Gharib , Rania Elsayed Hussein
246 1 5 _aتأثير الخلايا الجذعية المستخلصة من نخاع العظم علي قرح المعدة الناتجة عن الاندوميثاسين في فئران التجارب
260 _aCairo :
_bAzza Abusree Ahmed Elsaid ,
_c2014
300 _a160 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry
520 _aBackground: Peptic ulcer represents a serious medical problem due to their frequency among different socioeconomic classes. Although treatment with proton pump inhibitors (PPIs) and antibiotics has revolutionized the treatment of peptic ulcers, in some patients the ulcer is either refractory to conventional therapy, or recurs following successful initial treatment, leading to hemorrhagic complications. Refractory peptic ulcer remains a great challenge to gastroenterologists. Therefore, new alternative therapies for injured gastric mucosa are needed .The key factor in modulating microcirculation is nitric oxide (NO), Moreover, it plays a significant role in gastric ulcer healing. Also Bone marrow mesenchymal stem cells(BMMSCs) contribute to the formation of gastrointestinal tissues and has an important role in the healing of gut inuries. From this aspect we evaluated the effect of mesenchymal stem cells (MSCs) and NO on induced gastric ulcer rat model
530 _aIssued also as CD
653 4 _aGastric ulcer
653 4 _aMSCs
653 4 _aNO
700 0 _aDoaa Mostafa Gharib ,
_eSupervisor
700 0 _aLaila Ahmed Rashed ,
_eSupervisor
700 0 _aRania Elsayed Hussein ,
_eSupervisor
905 _aAml
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c48331
_d48331