000 019770000a22003490004500
003 EG-GICUC
005 20250223031112.0
008 060917s2006 ua a f m 000 0 eng d
040 _aEG-GICUC
_beng
_cEG-GICUC
041 0 _aEng
049 _aDeposite
097 _aM.Sc
099 _aCai01.12.10.M.Sc.2006.Am.U.
100 0 _aAmr Salah AbouZeid
245 1 0 _aNew routes for synthesis of biologically interestingpolyfunctional heteroaromatics utilizing an enamine precursor /
_cAmr Salah AbouZeid ; Supervised Mohamed Helmy Elnagdi , Fatma Mohamed Manhi
246 1 5 _aطرق جديدة لتخليق ا لحلقيات غير المتجانسة عديدة المجموعة الدالة وذات النشاط البيولوجى المتوقع باستخدام الاينامينات كمواد اولية
260 _aCairo :
_bAmr Salah AbouZeid ,
_c2006
300 _a157P :
_bill ;
_c30cm
502 _aThesis (M.Sc.) - Cairo University - Faculty Of Science - Department Of Organic Chemistry
520 _a2 - Acetylnaphthalene 1 condenses with dimethylformamide dimethylacetal (DMFDMA) yielding enaminone 2 , best yield was obtained by heating in a domestic microwave oven at full power for 5 minutes (85in hundred) The formed E enaminone 2 reacted with 2amino4methylthiazole 3 , 4aminopyridine 4 and Osubstituted aniline 5ac yielding the Z enaminones , predomination of Z form due to the fixation of this form by hydrogen bond (cfFigure 1) ; Although 2aminobenzothiazole 9 afforded a mixture of E enaminone 10 and Z - enaminone 11in ratio 4 : 6 as indicated from 1H NMR (cfFigure 2)
530 _aIssued also as CD
653 4 _aEnaminones
653 4 _apyrazoles
653 4 _apyrimidines
653 4 _aquinolinone
700 0 _aFatma Mohamed Manhi ,
_eSupervisor
700 0 _aMohamed Hilmy Elnagdi ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAmira
_eCataloger
905 _aMustafa
_eRevisor
942 _2ddc
_cTH
999 _c48444
_d48444