| 000 | 02796cam a2200349 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223031116.0 | ||
| 008 | 141204s2014 ua h f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.11.26.M.Sc.2014.En.D | ||
| 100 | 0 | _aEnas Ali Elsaftawy | |
| 245 | 1 | 0 |
_aDetermination of T cell lymphocytes population in urinary bladder biopsy material from schistosomiasis haematobium Egyptian patients / _cEnas Ali Elsaftawy ; Supervised Amany Ahmed Abdelaal , Ashraf Mohamed Emran , Abeer Said Alantably |
| 246 | 1 | 5 | _aتحديد شعبة الخلايا التائية الليمفاوية في عينات الخلايا المأخوذة من المثانة البولية من المرضي المصريين المصابين بالبلهارسيا البولية |
| 260 |
_aCairo : _bEnas Ali ElSaftawy , _c2014 |
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| 300 |
_a121 P. : _bfacsimiles ; _c25cm |
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| 502 | _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Parasitology | ||
| 520 | _aThe aim of the present study was to investigate in situ- expression of different markers related to T cell population Th1 (STAT4), Th2 (GATA3), Treg.(FOXP3) and T cytotoxic (CD8) in Egyptian patients suffering from chronic complicated schistosomiasis haematobium infection, using real time quantitative photocytometric analysis. On the other hand, to spot on the dominating T cell upon which the subsequent events had been built. Due to ethical consideration, the present work was applied only on tissue biopsies of the selected cases after cystectomy. Therefore, the existing research was built-in 29 schistosomiasis patients complicated with bladder cance. Cases in the present study were exposed to more or less continuous stimulation of Schistosoma egg antigen, either due to lack of treatment, failure of treatment or repeated exposure to infection. The cases in the current work were reported to be poorly controlled by unbalanced Th1/Th2 in which Th2 was dominated as proved by the significant higher expression level of GATA3 (Th2 marker) over STAT4 (Th1marker). In attempt to regain the control, Treg. (FOXP3) level was increased significantly, however, failed to dowen-regulate Th2(GATA3) which continue to expand resulting in more down-regulation of Th1 (STAT4) | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aQuantitative photocytometric | |
| 653 | 4 | _aSchistosomiasis haematobium | |
| 653 | 4 | _aT cell population | |
| 700 | 0 |
_aAbeer Said Alantably , _eSupervisor |
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| 700 | 0 |
_aAmany Ahmed Abdelaal , _eSupervisor |
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| 700 | 0 |
_aAshraf Mohamed Emran , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
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_aAml _eCataloger |
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_aNazla _eRevisor |
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| 942 |
_2ddc _cTH |
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| 999 |
_c48577 _d48577 |
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