000			02236cam a2200325 a 4500
003			EG-GiCUC
008			141214s2014 ua f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.08.05.Ph.D.2014.Fa.A
100	0		_aFaten Farouk Abdelfattah
245	1	0	_aApplication of liquid chromatography with different detection techniques to pharmaceutical analysis / _cFaten Farouk Abdelfattah ; Supervised Ramzia Ismail Elbagary , Hassan Mohamed Azzazy , Ehab Farouk ElKady
246	1	5	_aتطبيق طرق كروماتوجرافيا السوائل بتقنيات الكشف المختلفة على التحليل الصيدلى
260			_aCairo : _bFaten Farouk Abdelfattah , _c2014
300			_a275 P. ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry
520			_aIn this study, liquid chromatography with different detection techniques was employed for pharmaceutical analysis. The capabilities of ultra performance liquid chromatography (UPLC) coupled to MS / MS detector have been applied for pharmaceutical determinations. MS / MS detector depends on the mass / charge ratio (m/z) as a signal. It combines the advantages of the high sensitivity and specificity for the tested analytes. UPLC is the recent evolution in chromatography. It depends on decreasing the particle size of the stationary phase and thus improving the resolution and reduces analysis time. This advanced approach has been applied to separate pharmaceutical mixtures with greater efficiency and determination of UV silent aminoglycosides. The approach had been applied to separate drug impurities in trace amounts. Besides, this technique has been applied to the analysis of some drugs in plasma for toxicological and bioequivalence applications
530			_aIssued also as CD
653		4	_aBioequivalence
653		4	_aMS/MS
653		4	_aUPLC
700	0		_aEhab Farouk ElKady , _eSupervisor
700	0		_aHassan Mohamed Azzazy , _eSupervisor
700	0		_aRamzia Ismail Elbagary , _eSupervisor
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c48723 _d48723