000			02240cam a2200349 a 4500
003			EG-GiCUC
005			20250223031122.0
008			141217s2014 ua d f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.11.33.Ph.D.2014.Ah.S
100	0		_aAhmed Mohamed Eldeeb
245	1	0	_aSingle nucleotide polymorphism (SNP) rs8099917 as a predictive factor of virological response to pegylated interferon plus ribavirin in treatment of chronic hepatitis C virus patients / _cAhmed Mohamed Eldeeb ; Supervised Gamal Eldin Esmat , Wahid Halim Doss , Mohamed Ali Saber
246	1	5	_a استخدام النيكوليوتيد الفردى متعدد الأشكال (رس8099917) كوسيلة تنبؤية للاستجابة للانترفيرون طويل المفعول و الريبافيرين فى علاج مرضى فيروس سى الكبدى المزمن
260			_aCairo : _bAhmed Mohamed Eldeeb , _c2014
300			_a155 P. : _bcharts ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine
520			_aIntroduction: For SNP rs8099917, the favorable T allele is associated with a higher SVR after PEG - IFN alpha/RBV therapy while the G allele is a risk factor for non - response. Aim of work: Is to assess the value of (SNP) rs8099917 as a predictor of SVR. Methods: This study is a retrospective controlled study and was performed on a total number of 240 patients who were treated by PEG - IFN alpha/RBV for 48 weeks and (SNP) rs8099917 was done for the all patients. Results: TT genotype was more prevalent in SVR group than TG and GG genotypes. Conclusion: Determination of (SNP) rs8099917 before starting antiviral therapy may thus serve as a good response predictor
530			_aIssued also as CD
653		4	_aHCV
653		4	_aInterleukin 28b SNP rs8099917
653		4	_aPegylated interferon
700	0		_aGamal Eldin Esmat , _eSupervisor
700	0		_aMohamed Ali Saber , _eSupervisor
700	0		_aWahid Halim Doss , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c48781 _d48781