000 | 02240cam a2200349 a 4500 | ||
---|---|---|---|
003 | EG-GiCUC | ||
005 | 20250223031122.0 | ||
008 | 141217s2014 ua d f m 000 0 eng d | ||
040 |
_aEG-GiCUC _beng _cEG-GiCUC |
||
041 | 0 | _aeng | |
049 | _aDeposite | ||
097 | _aPh.D | ||
099 | _aCai01.11.33.Ph.D.2014.Ah.S | ||
100 | 0 | _aAhmed Mohamed Eldeeb | |
245 | 1 | 0 |
_aSingle nucleotide polymorphism (SNP) rs8099917 as a predictive factor of virological response to pegylated interferon plus ribavirin in treatment of chronic hepatitis C virus patients / _cAhmed Mohamed Eldeeb ; Supervised Gamal Eldin Esmat , Wahid Halim Doss , Mohamed Ali Saber |
246 | 1 | 5 | _a استخدام النيكوليوتيد الفردى متعدد الأشكال (رس8099917) كوسيلة تنبؤية للاستجابة للانترفيرون طويل المفعول و الريبافيرين فى علاج مرضى فيروس سى الكبدى المزمن |
260 |
_aCairo : _bAhmed Mohamed Eldeeb , _c2014 |
||
300 |
_a155 P. : _bcharts ; _c25cm |
||
502 | _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine | ||
520 | _aIntroduction: For SNP rs8099917, the favorable T allele is associated with a higher SVR after PEG - IFN alpha/RBV therapy while the G allele is a risk factor for non - response. Aim of work: Is to assess the value of (SNP) rs8099917 as a predictor of SVR. Methods: This study is a retrospective controlled study and was performed on a total number of 240 patients who were treated by PEG - IFN alpha/RBV for 48 weeks and (SNP) rs8099917 was done for the all patients. Results: TT genotype was more prevalent in SVR group than TG and GG genotypes. Conclusion: Determination of (SNP) rs8099917 before starting antiviral therapy may thus serve as a good response predictor | ||
530 | _aIssued also as CD | ||
653 | 4 | _aHCV | |
653 | 4 | _aInterleukin 28b SNP rs8099917 | |
653 | 4 | _aPegylated interferon | |
700 | 0 |
_aGamal Eldin Esmat , _eSupervisor |
|
700 | 0 |
_aMohamed Ali Saber , _eSupervisor |
|
700 | 0 |
_aWahid Halim Doss , _eSupervisor |
|
856 | _uhttp://172.23.153.220/th.pdf | ||
905 |
_aNazla _eRevisor |
||
905 |
_aSamia _eCataloger |
||
942 |
_2ddc _cTH |
||
999 |
_c48781 _d48781 |