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003 EG-GiCUC
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008 150207s2014 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.19.03.Ph.D.2014.Ma.R
100 0 _aMahmoud Aly Mohamed Ayoub
245 1 0 _aRole of single nucleotide polymorphism in DNA repair genes in cytogenetic status in acute myeloid leukemia patients /
_cMahmoud Aly Mohamed Ayoub ; Supervised Farida Hassan Gadallah , Gamal Thabet Ebid , Essam Hamed Elnoshokaty
246 1 5 _aالعلاقة بين الجينات المسئولة عن إصلاح الحمض النووى و مدى تأثيرها على التشوهات الوراثية لسرطان الدم الميلودى الحاد
260 _aCairo :
_bMahmoud Aly Mohamed Ayoub ,
_c2014
300 _a114 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Clinical Pathology
520 _aAcute myeloblastic leukemia (AML) is a clonal disorder characterized by acquisition of somatic mutations in haematopoietic progenitors cells. Defects in DNA repair genes and proteins associated with the regulation of repair are connected to many different human diseases including acute myeloid leukemia. Single nucleotide polymorphisms SNPs in many DNA repair genes revealed to be associated with cytogenetic abnormalities among newly diagnosed AML patients
530 _aIssued also as CD
653 4 _aAML
653 4 _aDNA repair
653 4 _aSNPs
700 0 _aEssam Hamed Elnoshokaty ,
_eSupervisor
700 0 _aFarida Hassan Gadallah ,
_eSupervisor
700 0 _aGamal Thabet Ebid ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c49264
_d49264