000			02148cam a2200337 a 4500
003			EG-GiCUC
005			20250223031143.0
008			150221s2014 ua o f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.08.05.M.Sc.2014.Ba.S
100	0		_aBasma Serag Eldin Alsayed Habib
245	1	0	_aSynthesis and biological evaluation of some novel phthalimide derivatives incorporated into other heterocycles as anticancer and antimicrobial agents / _cBasma Serag Eldin Alsayed Habib ; Supervised Kamelia Mahmoud Amin , Afaf Hussein Elmasry
246	1	5	_aالتشييد و التقييم البيولوجى لبعض مشتقات الفثاليميدات المرتبطة مع حلقات غير متجانسة كمضادات للسرطانات و الميكروبات
260			_aCairo : _bBasma Serag Eldin Alsayed Habib , _c2014
300			_a186 P. : _bphotographs ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry
520			_aThe phthalimide moiety has been utilized extensively in medicinal chemistry and is considered to be a privileged structure that shows various pharmacological activities including anti inflammatory, hypoglycemic, hypolipidemic, anticonvulsant, anxiolytic, antiviral, antitumor and antimicrobial activity. Therefore, we are considered with the synthesis of novel series of substituted (4- substituted phenylamino) methyl phthalimides with the objective of discovering novel antitumor antimicrobial agents. Moreover docking of the some biologically tested compounds into the active site of GyrB enzyme was performed to correlate the docking results with the biological results
530			_aIssued also as CD
653		4	_aPhthalimides
653		4	_aRing closure reactions
653		4	_aThiazoles and other heterocycles
700	0		_aAfaf Hussein Elmasry , _eSupervisor
700	0		_aKamelia Mahmoud Amin , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c49490 _d49490