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008 150222s2014 ua f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.18.04.M.Sc.2014.Ph.E
100 0 _aPhoebe Magdy Abdelmassieh Metias
245 1 0 _aEvaluation of Statistical Methods used in the Analysis of Competing Risks- In the Oro-Dental Field /
_cPhoebe Magdy Abdelmassieh Metias ; Supervised Amany Mousa Mohamed , Eman Hassan Anwar Aboulezz
246 1 5 _aتقييم الطرق الاحصائية المستخدمة فى تحليل المخاطر التنافسية فى مجال الفم والاسنان
260 _aCairo :
_bPhoebe Magdy Abdelmassieh Metias ,
_c2014
300 _a219 Leaves ;
_c30cm
502 _aThesis (M.Sc.) - Cairo University - Institute of Statistical Studies and Research - Department of Statistics and Econometrics
520 _aA topic that has received attention in both the statistical and medical literature is the estimation of the probability of failure for endpoints that are subject to competing risks. Methods of standard survival analysis such as the complement of Kaplan-Meier (KM) for estimation of cumulative incidence curves (1-KM), the log-rank test for comparison of these curves, and the standard Cox model for the assessment of covariates, are still used by medical researchers, however lead to biased and un interpretable results when an analysis focuses time-to-first event in scenarios where there are competing events. In thesis these standard survival methods are compared with other alternative methods as the cumulative incidence competing risks (CICR) curves, the Gray's test for comparing these curves, and the competing risks regression model (CRR).The data used included 348 patients with primary cancer of the oral cavity diagnosed at Tanta cancer center (TCC) during the period 2003-2007, data were analyzed using R program. The main aim is to attract the attention of medical researchers to use the appropriate statistical technique according to the nature of the available taking into consideration the presence of the competing risks. The Results showed that the incidence of each main outcome was overestimated by the standard methods
530 _aIssued also as CD
653 4 _aCompeting risk
653 4 _aCumulative incidence
653 4 _aKaplan-Meier curve
700 0 _aAmany Mousa Mohamed ,
_eSupervisor
700 0 _aEman Hassan Anwar Aboulezz ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAml
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c49524
_d49524