000			02232cam a2200337 a 4500
003			EG-GiCUC
005			20250223031144.0
008			150223s2014 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.12.21.Ph.D.2014.Za.E
100	0		_aZainab Zakaria Ali Zenhom
245	1	0	_aEvaluation of cell responses against hepatitis C virus antigens among Egyptian healthcare workers at high risk of infection / _cZainab Zakaria Ali Zenhom ; Supervised Mahmoud Ahmed Amer , Sayed Fekry Abdelwahab
246	1	5	_aتقييم رد الفعل الخلوى ضد أنتيجينات فيروس الإلتهاب الكبدى (سى) بين العاملين المصريين فى مجال الرعاية الصحية و المعرضين لمخاطر عالية من الإصابة بالعدوى
260			_aCairo : _bZainab Zakaria Ali Zenhom , _c2014
300			_a171 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Science - Department of Zoology
520			_aHepatitis C Virus (HCV) specific cell-mediated immunity (CMI) has been reported among exposed individuals without viremia or seroconversion. Limited data are available regarding CMI among at - risk, seronegative, aviremic Egyptian healthcare workers (HCW), where HCV genotype 4 predominates. We investigated CMI responses among HCW at the National liver institute, where over 85% of the patients are HCV - infected. We quantified HCV - specific CMI in 52 seronegative aviremic Egyptian HCW using an interferon gamma (IFN - Þ) enzyme-linked immunospot (ELISpot) assay in response to 7 HCV genotype 4a overlapping 15mer peptide pools covering most of the viral genome. We also characterized the phenotype of the responding T cells to the HCV peptide pools by flow cytometry
530			_aIssued also as CD
653		4	_aCell mediated immunity
653		4	_aHCV
653		4	_aHealthcare workers
700	0		_aMahmoud Ahmed Amer , _eSupervisor
700	0		_aSayed Fekry Abdelwahab , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c49527 _d49527