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| 003 | EG-GiCUC | ||
| 005 | 20250223031208.0 | ||
| 008 | 150404s2014 ua dh f m 000 0 eng d | ||
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_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.12.04.Ph.D.2014.No.E | ||
| 100 | 0 | _aNoha Mohamed Sayed Mohamed | |
| 245 | 1 | 0 |
_aEnhancement of cancer therapy using multifunctional gold nanoparticles formulations / _cNoha Mohamed Sayed Mohamed ; Supervised Ahmed soltan Monem , Nihal Saad Elbialy |
| 246 | 1 | 5 | _aتحسين علاج السرطان باستخدام تحضيرات جزيئات الذهب متعددة الوظائف |
| 260 |
_aCairo : _bNoha Mohamed Sayed Mohamed , _c2014 |
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| 300 |
_a207 P. : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biophysics | ||
| 520 | _aCurrent non-targeted chemotherapy and radiotherapy protocols causes marked cytotoxicity to critical organs in human. This thesis advances two multifunctional near infra-red (NIR) absorbing gold nanoparticles to target breast cancer cells in-vitro and Ehrlich carcinoma in-vivo. The two developed formulations, gold nanoshells with mesoporous silica core (PEG-DOX-MPS-GNSs) and gold nanorods coated mesoporous silica (pGNRs@mSiO2-DOX), can both convert near infrared light energy into heat causing thermal damage to cancerous cells. Further, the incorporated mesoporous silica exhibit high drug loading capacity that can specifically deliver the anticancer drug doxorubicin into tumor site and release it in response to the acidic tumor microenvironment | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aCancer | |
| 653 | 4 | _aChemotherapy | |
| 653 | 4 | _aGold nanoparticles | |
| 700 | 0 |
_aAhmed soltan Monem , _eSupervisor |
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| 700 | 0 |
_aNihal Saad Elbialy , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
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_aNazla _eRevisor |
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_aSoheir _eCataloger |
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_2ddc _cTH |
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_c50264 _d50264 |
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