| 000 | 02437cam a2200337 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223031214.0 | ||
| 008 | 150416s2014 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.08.09.M.Sc.2014.No.S | ||
| 100 | 0 | _aNoha Abdelfattah Fadel | |
| 245 | 1 | 0 |
_aStudy of the anti-inflammatory and analgesic effects of a certain natural product and selenium nanoparticles in experimentally induced models in gamma irradiated rats / _cNoha Abdelfattah Fadel ; Supervised Sanaa A. Kenawy , Mona A. Elghazaly |
| 246 | 1 | 5 | _aدراسة التأثير المضاد للإلتهاب و المسكن لمنتج طبيعى و النانو سيلينيوم فى النماذج المحدثة تجريبيا فى الجرذان المشععة |
| 260 |
_aCairo : _bNoha Abdelfattah Fadel , _c2014 |
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| 300 |
_a130 P. : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology | ||
| 520 | _aAim: To investigate the anti-inflammatory and analgesic effects of piperine and selenium nanoparticles (Nano-Se) using carrageenan-induced paw edema and hyperalgesia model and six-day old air pouch model in non-irradiated and irradiated rats. Materials and methods: Animals were exposed to a single radiation dose level of 6 Gy. Each of piperine 50 mg/kg, Nano Se 2.55 mg/kg and their combination was administered orally. In carrageenan-induced paw edema and hyperalgesia model, the paw volume and nociceptive threshold were measured 3 hours after carrageenan injection. In the six-days old air pouch model, the exudate was collected 6 hours after carrageenan injection for estimation of biochemical parameters. Results: The inflammatory but not the nociceptive response produced by carrageenan in irradiated rats was significantly higher than that induced in non-irradiated rats. Each of piperine, Nano-Se and their combination was effective in reducing the paw volume in non-irradiated and irradiated rats | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aInflammation | |
| 653 | 4 | _aPiperine | |
| 653 | 4 | _aÞ-radiation | |
| 700 | 0 |
_aMona A. Elghazaly , _eSupervisor |
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| 700 | 0 |
_aSanaa A. Kenawy , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aAml _eCataloger |
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| 905 |
_aNazla _eRevisor |
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| 942 |
_2ddc _cTH |
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| 999 |
_c50450 _d50450 |
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