000 02837cam a2200349 a 4500
003 EG-GiCUC
005 20250223031216.0
008 150419s2014 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.19.04.Ph.D.2014.Ah.E
100 0 _aAhmed Abdellatif Mohamed Abdelmawla
245 1 0 _aEvaluation of role of surgery in management of pediatric germ cell tumors according to risk adapted therapy protocols /
_cAhmed Abdellatif Mohamed Abdelmawla ; Supervised Amr Abdelmaged Atteia , Alaa Younes , lobna M. Elamin Shalaby
246 1 5 _aتقييم الدور الجراحى فى عالج أورام الخاليا الجرثومية فى الأطفال طبقا لبروتوكولات العلاج الملائمة لدرجة الورم
260 _aCairo :
_bAhmed Abdellatif Mohamed Abdelmawla ,
_c2014
300 _a187 P. :
_bfacsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Oncology (Surgical)
520 _aBackground: Malignant germ cell tumors (MGCTs) account for 3.5 % of all pediatric cancers These Patients typically have a bimodal age distribution, with a first peak during infancy and a second after the onset of puberty. GCTs are the most common malignant ovarian tumor in females aged <20 years. Sacrococcygeal and retroperitoneal abdominal tumors often achieve a large size prior to the onset of symptoms and the rate of metastases in these tumors is over 50% Methods: Patients with pediatric germ cell tumors presenting to children{u2019}s cancer hospital from 1st of January 2008 to end of June 2011 and those presenting to NCI and CCHE from end of June 2011 to end of December 2012. Patients underwent stratification according to risk into low, intermediate and high risk, all patients enrolled in this study will be analyzed for clinicopathologic features. Results: Out of 131 cases surgically explored only 26 cases had re exploration 8 cases explored for residual disease 9 cases for remote recurrence or metastatic disease and the other 9 cases for other complications. Out of 131 cases surgically managed only 12 cases had postoperative complications. Patients with low risk kept under follow up after surgery, out of those of low risk group (48 patients) only 8 patients (16.5%) shifted to intermediate risk chemotherapy
530 _aIssued also as CD
653 4 _aGerm cell tumors
653 4 _aPediatric
653 4 _aRisk protocols
700 0 _aAlaa Younes ,
_eSupervisor
700 0 _aAmr Abdelmaged Atteia ,
_eSupervisor
700 0 _alobna Mohamed Elamin Shalaby ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAml
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c50514
_d50514