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003 EG-GiCUC
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008 150428s2014 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.16.M.Sc.2014.Am.H
100 0 _aAmal Moulud Elhadi Shebani
245 1 0 _aHistological study on the effect of adipose tissue derived stem cells on the regeneration of injured skeletal muscle in a rat model /
_cAmal Moulud Elhadi Shebani ; Supervised Dina Mohamed Radwan , Mary Attia Morcos , Dalia Mohamed Elmarakby
246 1 5 _aدراسة هستولوجية عن تأثير الخلايا الجذعية المستخلصة من النسيج الدهني على تجدد العضلات الهيكلية المصابة في نموذج الجرذ
260 _acairo :
_bAmal Moulud Elhadi Shebani ,
_c2014
300 _a165 P. :
_bfacsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine- Department of Histalogy
520 _aMuscle injuries in sport activities can pose challenging problems in sports medicine. The best treatment for muscle injury has not been clearly established except for the conservative treatment that is routinely performed. The aim of the present study was to investigate whether adipose tissue derived stem cells (ASCs) could contribute to skeletal muscle healing. Thirty two adult male albino rats were included in the present study. They were classified into the following groups. Group1: served as control (sham) group. Group II; in which laceration was induced in the triceps muscle and rats were sacrificed 2, 4 weeks later (group IIa, IIb) respectively. Group III; stem cell treated group in which ASCs were injected at the site of laceration at a dose of one million cells for each rat and sacrificed 2,4 weeks later (group IIIa, IIIb). Skeletal muscle sections were stained with H & E stain, Masson{u2019}s trichrome stain, Prussian blue stain and immunohistochemical staining for CD-90 (stem cell marker) and VEGF. The number of centronucleated muscle fibers, the area% of collagen and VEGF immunoreactivity were measured using the image analyser
530 _aIssued also as CD
653 4 _aAdipose derived Stem cells
653 4 _aCD90
653 4 _aSkeletal muscle injury
700 0 _aDalia Mohamed Elmarakby ,
_eSupervisor
700 0 _aDina Mohamed Radwan ,
_eSupervisor
700 0 _aMary Attia Morcos ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAml
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c50674
_d50674