000 02650cam a2200325 a 4500
003 EG-GiCUC
008 150502s2014 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.09.08.Ph.D.2014.Ma.E
100 0 _aMarwa Mohamed Tawfiq Ali Abdalqader
245 1 4 _aThe effect of simvastatin gel in the treatment of intrabony defect in chronic periodontitis :
_bClinical, radiographic and immunohistochemical studies /
_cMarwa Mohamed Tawfiq Ali Abdalqader ; Supervised Azza Ezz Elarab , Kareman Said Elsoudany , Mohamed Khalifa Zayet
246 1 5 _aفعالية جل السيمفاستاتين فى علاج العيوب العظمية فى التهاب اللثة المزمن :
_bدراسة اكلينيكة و اشعاعية و مناعة هيستاكيمائية
260 _aCairo :
_bMarwa Mohamed Tawfiq Ali Abdalqader ,
_c2014
300 _a134 Leaves :
_bcharts , facsimiles ;
_c30cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Periodontology
520 _aThe present study was conducted to evaluate the effect of simvastatin gel in the treatment of intrabony defect in chronic periodontitis. The study was designed as split mouth in ten patients. Surgical procedure of open flap debridement was performed at affected sites to enable access to the defect. Simvastatin gel was delivered in ten sites and placement of placebo gel was done other ten sites. Pocket depth, clinical attachment level, plaque index, gingival index, linear measurements and bone density were recorded. Samples of gingival crevicular were collected at base line, 3 and 6 months postsurgically. Filter paper was used in samples collection and the samples were analyzed using ELISA technique to evaluate the level of osteopontin on the studied group. The statistical analysis showed that there was significant difference between a simvastatin group and placebo group in probing pocket depth, clinical attachment level, and bone density at the end of the study. The changes in the level of osteopontin were insignificant with simvastatin group at different follow up period. However it was significantly elevated in placebo group at 6 months
530 _aIssued also as CD
653 4 _aChronic periodontitis
653 4 _aOsteopontin OPN
653 4 _aSimvastatin SMV
700 0 _aAzza Ezz Elarab ,
_eSupervisor
700 0 _aKareman Said Elsoudany ,
_eSupervisor
700 0 _aMohamed Khalifa Zayet ,
_eSupervisor
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c50706
_d50706