000 02417cam a2200325 a 4500
003 EG-GiCUC
008 150704s2014 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.08.07.M.Sc.2014.Ra.P
100 0 _aRana Mohamed Ibrahim
245 1 0 _aPharmacognostical study of securigera securidaca (Linnaeus) degen and doerfler :
_bFamily fabaceae /
_cRana Mohamed Ibrahim ; Supervised Seham Salah Eldin Elhawary , Abdelrahman Omar Elshabrawy , Ali Mahmoud Elhalawany
246 1 5 _aدراسة عقاقيرية علي نبات حلبة الخيل (لينيه) ديجين و دورفيلر - العائلة البقلية
260 _aCairo :
_bRana Mohamed Ibrahim ,
_c2014
300 _a400 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacognosy
520 _aDNA and botanical profiling of Securigera securidaca L. were conducted. The lipoidal content of the flowers was investigated using GC/Ms analysis. Two compounds were isolated from n-hexane fraction of the flowers and identified as Ý-sitosterol and Ü-amyrin. One phenolic acid; salicylic acid was isolated from the methylene chloride fraction. Three flavonoids were isolated from the ethyl acetate fraction and identified as isovitexin, isoquercetrin and isorhamnetin-3-O-Ý-D-glucoside. Total flavonoids and phenolics were determined colorimetrically. The amount of total flavonoids was 48.82 ± 1.95 mg and total phenolics was 82.39 ± 2.79 mg per g of the dried powdered flowers. HPLC analysis of phenolic compounds present in the flowers revealed that isoquercetrin was the major flavonoid and syringic acid was the major phenolic acid. HPLC-DAD/ESI-MS analysis of the ethanolic extract of the flowers allowed the identification of 47 compounds including 39 flavonoids and 8 phenolic acids. One cardenolide was isolated from the immature fruits and identified as hyrcanoside
530 _aIssued also as CD
653 4 _aGC/MS
653 4 _aLlipoidal contents
653 4 _aSecurigera securidaca
700 0 _aAbdelrahman Omar Elshabrawy ,
_eSupervisor
700 0 _aAli Mahmoud Elhalawany ,
_eSupervisor
700 0 _aSeham Salah Eldin Elhawary ,
_eSupervisor
905 _aNazla
_eRevisor
905 _aSoheir
_eCataloger
942 _2ddc
_cTH
999 _c51518
_d51518