000 01937cam a2200349 a 4500
003 EG-GiCUC
005 20250223031245.0
008 150605s2014 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.28.M.Sc.2014.Fa.S
100 0 _aFatma Mostafa Ahmed Elelimy
245 1 0 _aStudy of growth differentiation factor 15 level in patients with beta thalassemia major /
_cFatma Mostafa Ahmed Elelimy ; Supervised Mona Hassan Eltagy , Mona Mohamed Hamdy , Nadia Ibrahim Sewilam
246 1 5 _aفى حالات انيميا البحر المتوسط GDF15دراسة
260 _aCairo :
_bFatma Mostafa Ahmed Elelimy ,
_c2014
300 _a103 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aBackground:The thalassemia syndromes represent the most common causes of ineffective erythropoiesis . The increased but ineffective erythropoiesis resulting in tissue iron overload induces numerous endocrine diseases, hepatic cirrhosis, cardiac failure and even death . Objectives: To study GDF15 levels in Ý- thalassemia major patients and to correlate its level to their iron status and different clinical and laboratory disease parameters. Conclusion:GDF15 level in our study represent a first step for its use as biomarker in thalassemia patients although future studies may be needed before its routine use
530 _aIssued also as CD
653 4 _aGDF15 gene
653 4 _aGrowth Differentiation Factor 15
653 4 _aThalassemia major
700 0 _aMona Hassan Eltagy ,
_eSupervisor
700 0 _aMona Mohamed Hamdy ,
_eSupervisor
700 0 _aNadia Ibrahim Sewilam ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSoheir
_eCataloger
942 _2ddc
_cTH
999 _c51549
_d51549