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008 150809s2014 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.19.M.Sc.2014.Sa.S
100 0 _aSarah Mahmoud Elsayed Ouda
245 1 0 _aSerum beta- 2 microglobulin level :
_bA possible marker for disease progression in Egyptian patients with chronic HCV related liver diseases /
_cSarah Mahmoud Elsayed Ouda ; Supervised Mikhail Nasr Mikhail , Ashraf Elsayed Abdelhamied , Ahmed Mohamed Khairy
246 1 5 _aبيتا-2 ميكروجلوبيولين المصلى :
_bدلالة ممكنة لتطور المرض عند المرضى المصريين المصابين بإلتهاب كبدى(ج) المزمن و أمراض الكبد المرتبطة بة
260 _aCairo :
_bSarah Mahmoud Elsayed Ouda ,
_c2014
300 _a158 P. :
_bcharts ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Microbiology and Immunology
520 _aBeta - 2 microglobulin (v2M) is responsible for transmission of viral antigens on the surface of cells as part of HLA complex. Normal serum levels are less than 3æg / ml. It increases in inflammatory and malignant conditions including HCV infection. Determining the concentration of serum v2M levels in patients with HCV related chronic hepatitis, cirrhosis, and hepatocellular carcinoma and correlate the results with clinical parameters for disease progression. In this analytical cross sectional study 92 participants were included in 4 equal groups: Group (1) non cirrhotic chronic HCV, Group (2):HCV related liver cirrhosis, Group (3): HCC on top of HCV, Group (4): healthy controls. History taking, clinical examination ,routine labs, and US were done to all patients. Group specific inclusion criteria: PCR, metavir score for group (1) patients. CT and AFP for Group (3) patients. v2M levels were measured in serum by ELISA. Quantitative variables presented by number and percent were compared by chi - square or fisher's exact test
530 _aIssued also as CD
653 4 _aHCC
653 4 _aHCV progression
653 4 _aSerum B2M
700 0 _aAhmed Mohamed Khairy ,
_eSupervisor
700 0 _aAshraf Elsayed Abdelhamied ,
_eSupervisor
700 0 _aMikhail Nasr Mikhail ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c51884
_d51884