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_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.12.21.Ph.D.2015.Mo.I | ||
| 100 | 0 | _aMostafa Abdelmaksoud Abdelhalim | |
| 245 | 1 | 0 |
_aImmunological modulation of auto-immune Systemic Lupus Erythematosus (SLE) infemale BWF1 mice Infected with malaria / _cMostafa Abd elmaksoud Abdelhalim ; Supervised Fathy Abdelghaffar,Azza Mohamed ElAmir , Gamal Badr Badr |
| 246 | 1 | 5 | _aالتغير المناعي الناتج عن إصابة إناث الفئران النيوزيلندية والتي تعد نموذجاً لمرض المناعة الذاتية الذئبة الحمراء: بالملاريا |
| 260 |
_aCairo : _bMostafa Abdelmaksoud Abdelhalim , _c2015 |
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| 300 |
_a178 P. : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Science - Department of Zoology | ||
| 520 | _aAutoimmune diseases are the third leading cause of morbidity and mortality, after heart disease and cancer, in the industrialized world. Systemic lupus erythematosus )SLE), is a prototypic multi-system autoimmune disease that can affect the heart, joints, skin, lungs, blood vessels, liver, kidneys, and nervous system. There is no one specific cause of SLE but the impact of infections on the development of SLE is substantial and the relationship between infections and autoimmunity in general is a complex phenomenon that has been the focus of much research. This study was designed to evaluate the effect of either live or gamma irradiated malaria infection on the autoimmune female BWF1 mice model of lupus. We observed many positive consequences of infection with live malaria parasite while gamma irradiation has diminished this effect. Some negative effects of infection were also observed. Taken together, our data reveal that infection of lupus mice with live malaria decrease apoptosis in renal tissue and confers protection against lupus nephritis the effect that couldn{u2019}t occur in case of gamma irradiated parasite infection | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aAutoimmune diseases | |
| 653 | 4 | _aMalaria | |
| 653 | 4 | _aSystemic lupus erythematosus | |
| 700 | 0 |
_aAzza Mohamed Elamir , _eSupervisor |
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| 700 | 0 |
_aFathy Abdelghaffar , _eSupervisor |
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| 700 | 0 |
_aGamal Badr , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
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_aAml _eCataloger |
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_aNazla _eRevisor |
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_2ddc _cTH |
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_c52238 _d52238 |
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