000			02154cam a2200325 a 4500
003			EG-GiCUC
008			151022s2015 ua d f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.08.08.M.Sc.2015.As.P
100	0		_aAsmaa Said Elshafei
245	1	0	_aPharmaceutical study on silica derivatives / _cAsmaa Said Elshafei ; Supervised Mohamed A. Elnabarawi , Ehab R. Bendas , Marwa Hassan Shukr
246	1	5	_aدراسة صيدلانية عن مشتقات السليكا
260			_aCairo : _bAsmaa Said Elshafei , _c2015
300			_a144 P. : _bcharts ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics
520			_aCreating predicting model that provides possibility to synthesize xerogels with controlled physiochemical properties thus controlled drug release according to chosen conditions is our goal. We studied the simultaneous effect of pH of the precursor solution, water: Tetraethylorthosilicate (TEOS) molar ratios, temperature, Polyethylene glycol (PEG) as additive and aqueous ammonia as aging solution on physiochemical properties of silica xerogel: surface area, total pore volume mesopore volume ,%of weight loss and total enthalpy, The silica xerogel was synthesized via acid catalyzed sol-gel method. Using 2 ⁵⁻² fractional factorial design to analyze the data. Samples were characterized by X-ray diffraction (XRD), High scanning electric microscopy (SEM), Fourier transformed infrared spectroscopy (FTIR), gas adsorption (N₂ at 77 K) and thermal analysis including; thermogravimetric analysis, differential thermal analysis and Differential scanning calorimetry (TGA, DTA and DSC)
530			_aIssued also as CD
653		4	_aFractional factorial design
653		4	_aSilica xerogels nanoparticles
653		4	_aSynthesis conditions
700	0		_aEhab R. Bendas , _eSupervisor
700	0		_aMarwa Hassan Shukr , _eSupervisor
700	0		_aMohamed A. Elnabarawi , _eSupervisor
905			_aAml _eCataloger
905			_aNazla _eRevisor
942			_2ddc _cTH
999			_c52882 _d52882