| 000 | 02685cam a2200349 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223031335.0 | ||
| 008 | 151114s2015 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.11.18.Ph.D.2015.Sa.R | ||
| 100 | 0 | _aSahar Abdelnasser Ahmed | |
| 245 | 1 | 0 |
_aRenal expression, serum and urinary levels of HMGB1 in SLE with and without lupus nephritis / _cSahar Abdelnasser Ahmed ; Supervised Aysha I. Z. Badawi , Hanan Hassan fouad , Randa fayez |
| 246 | 1 | 5 | _aفي النسيج الكلوى و نسبته فى الدم و البول فى التهاب الكلى المصاحب لمرض الذئبة الحمراء الجهازى و فى حالات الذئبة الحمراء الجهازى الغير مصحوبة بالتهاب بالكلى HMGB1دلاله |
| 260 |
_aCairo : _bSahar Abdelnasser Ahmed , _c2015 |
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| 300 |
_a255 P. : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Internal Medicine | ||
| 520 | _aBackground: Systemic Lupus Erythematosus (SLE) is a systemic autoimmune disease characterised by involvement of multiple organ systems. Its aetiology is largely unknown; however, genetic and environmental factors are proposed to contribute to breaking tolerance, resulting in the production of a variety of antibodies directed to self-components. (Qing et al 2008) {uF0D8}Study design: Case control study. {uF0D8}Subject:61 Systemic lupus patients fulfilling the classification criteria for the diagnosis of SLE (Bombardier et al 1992) ,will be selected from Internal Medicine Department, Kasr Al-Aini Hospital, Cairo University after ethical committee approval and getting written informed consent from each patient. {uF0D8}Objectives: To assess the potential role of HMGB1 in SLE and whether urinary and serum levels of HMGB1 reflect renal inflammation and correlate with disease activity, we aim of this study to investigate renal tissue expression of HMGB1 as well as serum and urinary levels of HMGB1 in correlation with renal histopathological changes and clinical and serological disease activity in SLE patients with and without LN in comparison to healthy controls (HC). | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aHMGB1 | |
| 653 | 4 | _aLupus nephritis | |
| 653 | 4 | _aSLE | |
| 700 | 0 |
_aAysha Ibrahim Z. Badawi , _eSupervisor |
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| 700 | 0 |
_aHanan Hassan fouad , _eSupervisor |
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| 700 | 0 |
_aRanda fayez , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aNazla _eRevisor |
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| 905 |
_aSoheir _eCataloger |
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| 942 |
_2ddc _cTH |
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| 999 |
_c53282 _d53282 |
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