000 02052cam a2200349 a 4500
003 EG-GiCUC
005 20250223031340.0
008 151123s2015 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.08.03.M.Sc.2015.Mo.A
100 0 _aMoataz Abdalla Yehia
245 1 0 _aAnalytical study for tadalafil (Cialis®) and equivalent compounds /
_cMoataz Abdalla Yehia ; Supervised Mohamed Abdelkawy Ibrahim , Mohamed Abdalla Elsayed , Mamdouh Reda Rezk
246 1 5 _aدراسة تحليلية للتادالافيل (سيالس) و بعض المركبات الشبيهه
260 _aCairo :
_bMoataz Abdalla Yehia ,
_c2015
300 _a211 P. :
_bcharts ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry
520 _aFour different stability indicating assay methods were developed and validated for the determination of (tadalafil, sildenafil and terazosin) in the presence of its degradation product. The first and second methods was based on the derivative and derivative ratio spectrophotometric technique using acetonitrile: water mixtrure {u2160}:{u2160} for tadalafil and methanol as a solvent for both sildenafil and terazosin. In the third method, we used TLC - densitometric technique using high performance thin - layer chromatography plates with a developing system consisting of {chloroform: acetone: ammonia (9: 1: 0.1, by volume)}, {chloroform: toluene: ethanol: acetic acid(3: 3: 4: 0.1, by volume)} and choloroform: acetone: ammonia 6: 4: 0.1, by voiumes
530 _aIssued also as CD
653 4 _aCialis®
653 4 _aEquivalent compounds
653 4 _aTadalafil
700 0 _aMamdouh Reda Rezk ,
_eSupervisor
700 0 _aMohamed Abdalla Elsayed ,
_eSupervisor
700 0 _aMohamed Abdelkawy Ibrahim ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c53463
_d53463