000 | 02361cam a2200325 a 4500 | ||
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003 | EG-GiCUC | ||
008 | 151123s2015 ua dh f m 000 0 eng d | ||
040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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041 | 0 | _aeng | |
049 | _aDeposite | ||
097 | _aPh.D | ||
099 | _aCai01.11.28.Ph.D.2015.Ha.M | ||
100 | 0 | _aHala Mohsen Abdulsalam Abdullatif | |
245 | 1 | 2 |
_aA molecular study of mitochondrial hepatopathies in neonates and infants with liver cell failure / _cHala Mohsen Abdulsalam Abdullatif ; Supervised Nabil Abdelaziz Mohsen , Hanaa Mostafa Elkaraksy , Rokaya Elsayed Mohsen |
246 | 1 | 5 | _aدراسة جزئية لأمراض المتقدرة (الميتوكوندريا) بالكبد فى حديثى الولادة و الأطفال المصابين بفشل فى الكبد |
260 |
_aCairo : _bHala Mohsen Abdulsalam Abdullatif , _c2015 |
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300 |
_a134 P. : _bcharts , facsimiles ; _c25cm |
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502 | _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics | ||
520 | _aAcute liver failure (ALF) in neonates and infants is a life threatening disease. Systematic evaluation of the etiology of ALF may help in establishing a diagnosis and thus guiding treatment decisions. To identify the etiological diagnosis of acute liver failure in neonates and infants; in addition to determining the frequency of DGUOK related mitochondrial DNA depletion syndromes. A cross sectional study carried out at Cairo university children{u2019}s hospital from January 2013 to December 2014. All neonates and infants who presented with acute liver failure and cholestasis with early onset liver failure were included. Acyclovir and lactose free formula were started after drawing samples for HSV and galactose - 1- phosphate. Investigations were tailored according to the patient{u2019}s condition. Mitochondrial DNA content and its percent of control were measured. Amplification of coding regions in DGUOK gene was done using high resolution melting analysis technique | ||
530 | _aIssued also as CD | ||
653 | 4 | _aLiver cell failure | |
653 | 4 | _aMitochondrial | |
653 | 4 | _aNeonates | |
700 | 0 |
_aHanaa Mostafa Elkaraksy , _eSupervisor |
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700 | 0 |
_aNabil Abdelaziz Mohsen , _eSupervisor |
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700 | 0 |
_aRokaya Elsayed Mohsen , _eSupervisor |
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905 |
_aNazla _eRevisor |
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905 |
_aSamia _eCataloger |
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942 |
_2ddc _cTH |
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999 |
_c53470 _d53470 |