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008 160127s2014 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.12.21.Ph.D.2014.El.E
100 0 _aElshaimaa Mohsen Ibrahim Mostafa
245 1 4 _aThe effect of curcumin on type 17 helper T cells in collagen-induced arthritis in rats /
_cElshaimaa Mohsen Ibrahim Mostafa ; Supervised Somaya Eldeeb , Amany Elwakkad , Abeer Badr
246 1 5 _aثأثير الكركمين على نوع الخلايا تى 71 المساعدة في التهاب المفاصل المستحث بالكولاجين في الجرذان
260 _aCairo :
_bElshaimaa Mohsen Ibrahim Mostafa ,
_c2014
300 _a224 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Science - Department of Zoology
520 _aRheumatoid arthritis (RA) is one of the major human systemic autoimmune diseases, affecting approximately 1% of the world population, with unknown etiology attacking synovial joints, causing bone erosion, which leads to joint deformation, fractures and severe disability. For which there is no effective cure available. CIA was chosen as an animal model of RA as it produces many of the clinical and pathological features of human RA. Male albino rats were divided into 7 groups: N, D, A, Cb, Ca, M and CM. Treatments in groups Ca, M and CM were initiated from day 20 and continued till day 69. Blood samples were collected on days 0, 20, 41, 48, 61 and 69 post-induction, and serum levels of IL-17, IL-23, IL-27, IFN-y and TGF-ß were measured. Rats were sacrificed on the 69th day and thymus, lung, liver, spleen, kidney and hind paws were collected for histopathological examination
530 _aIssued also as CD
653 4 _aCIA
653 4 _aMTX
653 4 _aRA
700 0 _aAbeer Badr ,
_eSupervisor
700 0 _aAmany Elwakkad ,
_eSupervisor
700 0 _aSomaya Eldeeb ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAml
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c54752
_d54752