000 | 02398cam a2200349 a 4500 | ||
---|---|---|---|
003 | EG-GiCUC | ||
005 | 20250223031421.0 | ||
008 | 160202s2015 ua h f m 000 0 eng d | ||
040 |
_aEG-GiCUC _beng _cEG-GiCUC |
||
041 | 0 | _aeng | |
049 | _aDeposite | ||
097 | _aM.Sc | ||
099 | _aCai01.10.13.M.Sc.2015.Am.S | ||
100 | 0 | _aAmani Magdi Nagi Mahmoud | |
245 | 1 | 0 |
_aSimvastatin as a growth promoting material on the healing of critical sized bone defect in dogs: _bAn experimental study / _cAmani Magdi Nagi Mahmoud ; Supervised Mohamed Ayad Abdehamid , Elham A. Hassan , Iman Bakr Shaheed |
246 | 1 | 5 |
_aالسيمفاستاتين كمادة محفزة للنمو لالتئام النواقص العظمية الحرجة في الكلاب : _b دراسة تجريبية |
260 |
_aCairo : _bAmani Magdi Nagi Mahmoud , _c2015 |
||
300 |
_a98 P. : _bfacsimiles ; _c25cm |
||
502 | _aThesis (M.Sc.) - Cairo University - Faculty of Veterinary Medicine - Department of Surgery , Anesthesiology and Radiology | ||
520 | _aCritical size defect represents a major challenge in orthopedic surgery. The aim of the work was decided to study the effect of locally applied simvastatin as a growth promoting material on the healing of experimentally induced critical size bone defect in dogs. A prospective experimental study was done on 18 skeletally mature male mongrel dogs. A 21 mm mid-shaft femoral defect was induced in all dogs. Dogs were randomly allocated into one of the two groups; group 1:- simvastatin was locally applied into the defect site, group 2:- defects were kept without simvastatin (sham-operated group). All defect sites were stabilized using bone plate and screws. Dogs were evaluated clinically and radiographically every two weeks till 12 weeks. The dogs were euthanized at 4,8 and 12 weeks for gross pathologic and histopathologic examination (Hematoxyline & Eosin, Masson Trichrome, Alizarine red and immune histochemical evaluation (osteopontin) | ||
530 | _aIssued also as CD | ||
653 | 4 | _aCritical sized bone defect | |
653 | 4 | _aHealing | |
653 | 4 | _aSimvastatin | |
700 | 0 |
_aElham A. Hassan, _eSupervisor |
|
700 | 0 |
_aIman Bakr Shaheed , _eSupervisor |
|
700 | 0 |
_aMohamed Ayad Abdelhamid , _eSupervisor |
|
856 | _uhttp://172.23.153.220/th.pdf | ||
905 |
_aAml _eCataloger |
||
905 |
_aNazla _eRevisor |
||
942 |
_2ddc _cTH |
||
999 |
_c54879 _d54879 |