000 02481cam a2200325 a 4500
003 EG-GiCUC
008 160214s2015 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.19.04.M.Sc.2015.Ah.T
100 0 _aAhmed Tarek Hashem
245 1 0 _aTreatment outcome in patients with metastatic head and neck cancer /
_cAhmed Tarek Hashem ; Supervised Magdy Mohamed Saber , Hanan Ramadan Nassar , Mosaad Elgammal
246 1 5 _aنتائج علاج حالات أورام الرأس والرقبة المنتشرة
260 _aCairo :
_bAhmed Tarek Hashem ,
_c2015
300 _a134 P. :
_bcharts ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - National Cancer Institute - Department Oncology (Medical)
520 _aIntroduction: Therapy for head and neck cancers has evolved over the past decade, but few detailed analyses of recent developments in survival on the population level have been published. Aim of work: The purpose of our study was to evaluate the treatment outcomes in patients with metastatic / recurrent head and neck cancer. Patients & Methods: We performed a retrospective analysis on 73 patients treated between 2009 and 2011 at the NCI & NICC. The treatment outcome was evaluated according to patient and disease criteria in the form of relapse rate (of initial treatment), Clinical response, PFS and OS. Results: Although statistically insignificant a small difference was found in DFS between patients who had surgical intervention and those who received only chemo-radiotherapy.The most affected and significant measures of treatment outcome found were relapse rate occurred in 47 patients (65.7%) and median OS of 36 months (the OS was measured from the initial treatment for all the patients). when related to patient and disease criteria the relapse rate was high in female gender, younger age (60 years or younger), When considering the tumor-related factors, hypopharyngeal tumor site, Grade II, T3 tumor size and LN positivity were associated with the highest rate of relapse
530 _aIssued also as CD
653 4 _aNeck Cancer
653 4 _aPatients With Metastatic Head
653 4 _aTreatment
700 0 _aHanan Ramadan Nassar ,
_eSupervisor
700 0 _aMagdy Mohamed Saber ,
_eSupervisor
700 0 _aMosaad Elgammal ,
_eSupervisor
905 _aAml
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c54959
_d54959