| 000 | 02679cam a2200349 a 4500 | ||
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| 003 | EG-GiCUC | ||
| 005 | 20250223031425.0 | ||
| 008 | 160217s2015 ua h f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.11.28.M.Sc.2015.Mo.E | ||
| 100 | 0 | _aMohamed Salah Thabet | |
| 245 | 1 | 0 |
_aEfficacy and safety of milrinone versus sildenafil in the management of moderate to severe peristent pulmonary hypertention in neonates / _cMohamed Salah Thabet ; Supervised Zahraa Mohamed Ezz Eldein , Hanan Zekry Khaled , Tamer Abdelhamed Dihome |
| 246 | 1 | 5 | _aدراسة مدى كفاءة و مدى امان عقار الميلرينون وعقارالسيلدنافيل في علاج إرتفاع ضغط الشريان الرئوي في الاطفال حديثي الولاده |
| 260 |
_aCairo : _bMohamed Salah Thabet , _c2015 |
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| 300 |
_a123 P. : _bfacsimiles ; _c25cm |
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| 502 | _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics | ||
| 520 | _aBackground: Pulmonary hypertension in newborn (PPHN) is a critical problem facing neonatologists. Aim of the work: To determine the impact of management strategies on the outcome of PPHN. Patients and methods: Prospective descriptive study. 40 neonates with the diagnosis of PPHN who were admitted in NICUs in multi-centers from June 2014 to December 2014. Neonates divided into 2 equal groups one is treated by intravenous milrinone infusion and the other is treated by nasogastric sildenafil, it includes 33 males, 7 females; their mean gestational age was ±36.5weeks and the mean weight was 2.9 ± 0.5Kg. Results: Male neonates had higher incidence of PPHN 82.5% compared to females 17.5% .Neonates recived intravenous milrinone infusion shows statistical significant improvement than those recived nasogastric sildenafil in oxygenation index (OI)values 24 hrs after treatment(p{u2264}0.010), 48 hrs later (P{u2264} 0.001). Successful treatment was defined as drop of systolic pulmonary artery pressure (SPAP) below {u2264}40mmHg. There was statistical significant drop of SPAP after application ofmilrinone than sildenafil (P{u2264}0.040). The mortality rate was 10/40 neonates (25%) | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aBlood gases | |
| 653 | 4 | _aPPHN | |
| 653 | 4 | _aSystolic pulmonary artery pressure | |
| 700 | 0 |
_aHanan Zekry Khaled , _eSupervisor |
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| 700 | 0 |
_aTamer Abdelhamed Dihome , _eSupervisor |
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| 700 | 0 |
_aZahraa Mohamed Ezzeldein , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
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_aAml _eCataloger |
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_aNazla _eRevisor |
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_2ddc _cTH |
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_c55031 _d55031 |
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