000 | 02424cam a2200349 a 4500 | ||
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003 | EG-GiCUC | ||
005 | 20250223031427.0 | ||
008 | 160221s2015 ua dh f m 000 0 eng d | ||
040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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041 | 0 | _aeng | |
049 | _aDeposite | ||
097 | _aPh.D | ||
099 | _aCai01.11.07.Ph.D.2015.Ne.A | ||
100 | 0 | _aNeveen Ahmed Ahmed Khalil | |
245 | 1 | 0 |
_aAssociation study of uncouplingprotein2 polymorphism with myeloperoxidase in diabetic patients type 2 / _cNeveen Ahmed Ahmed Khalil ; Supervised Iman Atef Mandour , Khadiga Muhammad Abugabal , Hanan Muhammad Farhan |
246 | 1 | 5 | _aالعلاقة بين تعدد اشكال الجين فك ربط البروتين 2 و الانزيم ميلوبيرؤكسيديز فى مرضي السكرى النوع الثاني |
260 |
_aCairo : _bNeveen Ahmed Ahmed Khalil , _c2015 |
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300 |
_a97 P. : _bcharts , facsimiles ; _c25cm |
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502 | _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology | ||
520 | _aBackground :It is well established that genetic factors play an important role in the development of type 2 diabetes (T2D) and its chronic complications. Uncoupling protein 2 (UCP2) is expressed in several tissues, and acts in the protection against oxidative stress, some studies have reported the common polymorphisms in UCP2 gene -866G/A is possibly associated with cardiovascular complication of diabetic patients with inconclusive results. Myeloperoxidase (MPO) plays an important role in the initiation, progression, and the complications of atherosclerosis. It is one of the most promising biomarkers of oxidative stress for clinical cardiologists . Objective: The objective of this study was to evaluate the association between UCP2 gene, -866G/A polymorphism with cardiovascular disease and obesity in diabetic patients type2 and role of MPO in cardiovascular disease in diabetic patients, also the association between MPO and UCP2 gene polymorphism in diabetic patients | ||
530 | _aIssued also as CD | ||
653 | 4 | _aCVD | |
653 | 4 | _aMPO | |
653 | 4 | _aUCP2 gene polymorphism | |
700 | 0 |
_aHanan Muhammad Farhan , _eSupervisor |
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700 | 0 |
_aIman Atef Mandour , _eSupervisor |
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700 | 0 |
_aKhadiga Muhammad Abugabal , _eSupervisor |
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856 | _uhttp://172.23.153.220/th.pdf | ||
905 |
_aNazla _eRevisor |
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905 |
_aSoheir _eCataloger |
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942 |
_2ddc _cTH |
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999 |
_c55095 _d55095 |