000			02584cam a2200337 a 4500
003			EG-GiCUC
005			20250223031430.0
008			160224s2015 ua d f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.12.08.M.Sc.2015.Ve.D
100	0		_aVeronia Nabil Abdrabou
245	1	0	_aDetermination of mbeverine hydrochloride drug using Ion selective electrodes / _cVeronia Nabil Abdrabou ; Supervised Mohamed Mohamed Omar , Awad Alsyed Ali Signature
246	1	5	_aتقدير دواء الميبفرين هيدروكلورايد باستخدام الأقطاب الأيونيه الأنتقائيه
260			_aCairo : _bVeronia Nabil Abdrabou , _c2015
300			_a142 P. : _bcharts ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Science- Department of Analytical Chemistry
520			_aA simple, rapid and sensitive method for the determination of mebeverine hydrochloride (MBHC) in urine, serum and pharmaceutical preparations using modified carbon paste and screen printed electrodes was developed. The electrochemical sensors showed a linear dynamic range of 3.0 {u00D7} 10⁻⁷ {u2013} 1.0 {u00D7} 10⁻² , 1.0 {u00D7} 10⁻⁷ {u2013} 1.0 {u00D7} 10⁻² for MCPEs ( sensor I, II) and 1.0 {u00D7} 10⁻⁷ {u2013} 1.0 {u00D7} 10⁻² mol L⁻¹ for both MSPEs (sensor II, IV) with detection limit of 3.0{u00D7}10-7 and 1{u00D7}10⁻⁷ mol L-1 for modified carbon paste and screen printed (MCPEs; sensors I ,II MSPEs; III,IV), respectively. The slopes of the calibration graphs are 56.78±0.85, 58.80±0.46, 56.49±0.85 and 57.93±0.46 mV decade-1 for MCPEs and MSPEs with tricresylphosphate (TCP) (sensor I, III), o-nitrophenyloctylether (o-NPOE) (sensor II, IV) as plasticizers, respectively. The response time was relatively quick in the whole concentration range (8, 7, 7 and 6 s) for electrodes I, II, III and IV, respectively. The electrodes can be used at least 65, 73, 140 and 159 days without observing any deviations in a pH range of 2.0 to 8.0 , 1.5 to 8.0, 1.5 to 8.0 and 1.5 to 8.5 for electrodes I , II, III and IV, respectively
530			_aIssued also as CD
653		4	_aMebeverine ion-selective electrodes
653		4	_aModified carbon paste sensors
653		4	_aPharmaceutical preparations
700	0		_aAwad Alsyed Ali Signature , _eSupervisor
700	0		_aMohamed Mohamed Omar , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aAml _eCataloger
905			_aNazla _eRevisor
942			_2ddc _cTH
999			_c55171 _d55171