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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.28.M.Sc.2015.No.I
100 0 _aNora Mohammed Hussein
245 1 4 _aThe influence of phototherapy on serum cytokine concentrations in newborn infants /
_cNora Mohammed Hussein ; Supervised Laila Hussein Mohammed , Fatma A. Fathi El Mogy , Nermin Ramy M. Kamel
246 1 5 _aتأثير العلاج الضوئي على تركيزات السيتوكينات في الأطفال حديثي الولادة
260 _aCairo :
_bNora Mohammed Hussein ,
_c2015
300 _a95 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aNeonatal jaundice in the first week of life is a common problem in newborns.The most important intervention for infants with severe hyperbilirubinemia is to initiate phototherapy without delay. Although phototherapy is the standard treatment for neonatal hyperbilirubinemia, it may lead to potential side effects such as retinal degeneration, diarrhea, dehydration, and skin rash. Phototherapy treatment can affect the function of the immune system in newborns via alterations in cytokine production. Objectives:In our study we hypothized that phototherapy can affect the level of pro-inflammatory and anti- inflammatory cytokines. We choosed interleukin 6 (pro-inflammatory) and interleukin 10 (anti-inflammatory) to study this effect because they are produced by keratinocytes. Results: our study revealed an increase in serum level of IL6 after treatment with phototherapy. However no change was observed for IL 10 between basal values and treatment with statistically significant Pvalue for IL-6 statistically insignificant for IL-10. Conclusions: Phototherapy used in the treatment of neonatal hyperbilirubinemia can affect the level of cytokines but as the previous studies were not homogenous so more studies are needed to be done to study the effect of phototherapy on serum cytokines concentration in the newborn
530 _aIssued also as CD
653 4 _aInterleukin
653 4 _aNNJ
653 4 _aPototherapy
700 0 _aFatma Ahmed Fathi El Mogy ,
_eSupervisor
700 0 _aLaila Hussein Mohammed ,
_eSupervisor
700 0 _aNermin Ramy Mohamed Kamel ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSoheir
_eCataloger
942 _2ddc
_cTH
999 _c55303
_d55303