000 | 02399cam a2200349 a 4500 | ||
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003 | EG-GiCUC | ||
005 | 20250223031442.0 | ||
008 | 160316s2015 ua f m 000 0 eng d | ||
040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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041 | 0 | _aeng | |
049 | _aDeposite | ||
097 | _aM.Sc | ||
099 | _aCai01.11.10.M.Sc.2015.Fa.S | ||
100 | 0 | _aFatma Hany Abdelrahman Makroum | |
245 | 1 | 0 |
_aSerum and tissue 2LIGHT3 levels in patients with multiple or recurrent verruca vulgaris / _cFatma Hany Abdelrahman Makroum ; Supervised Manal A-W Bosseila , Dina M. Kadry , Olfat G. Shaker |
246 | 1 | 5 | _aمستوى مادة اللايت فى المصل و الجلد للمرضى المصابين بالثآليل الفيروسية المتعددة أو المتكررة |
260 |
_aCairo : _bFatma Hany Abdelrahman Makroum , _c2015 |
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300 |
_a127 P. ; _c25cm |
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502 | _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venereology | ||
520 | _aWarts are benign lesions caused by human papilloma virus (HPV). Host defense against HPV relies on intact and functioning cellular immunity including T cell and natural killer (NK) cell cytotoxicity. Therefore, in patients in whom warts are severe or recalcitrant, concern for immune defects is raised. LIGHT (LT - like, exhibits inducible expression and competes with HSV glycoprotein D for herpes virus entry mediator (HVEM), a receptor expressed by T lymphocytes) signaling is important for cell survival, inflammation, and tumor eradication. Based on previous studies suggesting a role of LIGHT in control of intracellular infections as M. tuberculosis infection, we hypothesize that LIGHT may contribute to control of HPV infection. To identify the role of cell-mediated immunity, expressed as LIGHT level, in cases of multiple / recurrent verrucae, and to assess whether the immune response is decreased at local level in the skin only, or whether a systemic diminution in cell-mediated immunity is associated in such cases | ||
530 | _aIssued also as CD | ||
653 | 4 | _aLIGHT | |
653 | 4 | _aSerum | |
653 | 4 | _aTissue | |
700 | 0 |
_aDina Mohamed Kadry , _eSupervisor |
|
700 | 0 |
_aManal Abdelwahed Bosseila , _eSupervisor |
|
700 | 0 |
_aOlfat Gamil Shaker , _eSupervisor |
|
856 | _uhttp://172.23.153.220/th.pdf | ||
905 |
_aNazla _eRevisor |
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905 |
_aSamia _eCataloger |
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942 |
_2ddc _cTH |
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999 |
_c55566 _d55566 |