| 000 | 02443cam a2200349 a 4500 | ||
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| 003 | EG-GiCUC | ||
| 005 | 20250223031451.0 | ||
| 008 | 160406s2015 ua dh f m 000 0 eng d | ||
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_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.12.21.Ph.D.2015.He.T | ||
| 100 | 0 | _aHeba Ali Abdelrahman Shalabi | |
| 245 | 1 | 0 |
_aTeratogenic effects of bronchodilators drug on the pregnant female of albino rats and their offsprings / _cHeba Ali Abdelrahman Shalabi ; Supervised Abdelwahab A. Elghareeb , Sayed Fahim Tahaa , Alaa A. Shamkh |
| 246 | 1 | 5 | _aالتأثيرات المشوهة لأدوية موسعات الشعب على إناث الفئران الحوامل ونسلها |
| 260 |
_aCairo : _bHeba Ali Abdelrahman Shalabi , _c2015 |
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| 300 |
_a260 Leaves : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Science - Department of Zoology | ||
| 520 | _aThe present study aimed to evaluate the teratogenic effects of the mucolytic and broncholytic drug (Mucophylline) is daily oral administered to the pregnant albino rats. The pregnant animals treated during the gestational period (5th {u2013} 19th day of gestation) with doses 30.83 mg/Kg and 66.61 mg/Kg (human equivalent dose). On the 20th day of gestation, the animals were sacrificed and the numbers of implanation sites, resorbed and live fetuses were counted. The placental weight, fetal weight, length and tail length were recorded. The external morphology and skeletal malformations, histological studies of placenta, brain, liver and kidney of mother and fetus were evaluated. Also the oxidative stress markers were evaluated. Results showed decreased weight gain, fetal growth retardation during gestation period was dose dependent. Hematoma and anomalies of limbs were detected morphologically in the fetuses of maternally treated groups. Fetal skeletal abnormalities included lack of bones ossification and bent ribs. | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aPregnant albino rats | |
| 653 | 4 | _aSkeletal malformation | |
| 653 | 4 | _aTeratogenecity | |
| 700 | 0 |
_aAbdelwahab A. Elghareeb , _eSupervisor |
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| 700 | 0 |
_aAlaa Abdelhamed Shamkh , _eSupervisor |
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| 700 | 0 |
_aSayed Fahim Tahaa , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
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_aNazla _eRevisor |
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| 905 |
_aSoheir _eCataloger |
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| 942 |
_2ddc _cTH |
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_c55872 _d55872 |
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