000 | 02885cam a2200349 a 4500 | ||
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003 | EG-GiCUC | ||
005 | 20250223031451.0 | ||
008 | 160406s2015 ua h f m 000 0 eng d | ||
040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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041 | 0 | _aeng | |
049 | _aDeposite | ||
097 | _aM.Sc | ||
099 | _aCai01.11.10.M.Sc.2015.He.E | ||
100 | 0 | _aHeba Ibrahem Mahmoud Moftah | |
245 | 1 | 0 |
_aEffect of photochemotherapy on cardiometabolic markers in patients with psoriasis with and without atherosclerosis / _cHeba Ibrahem Mahmoud Moftah ; Supervised Wedad Zoheir Mostafa , Vanessa Galal Hafez, SaharAbdelatty |
246 | 1 | 5 | _a دراسة تأثير الأشعة فوق البنفسجية (أ) + سورالين على دلالات الأيض والقلب فى مرضى الصدفية المصابين بتصلب الشرايين وغير المصابين بتصلب الشرايين |
260 |
_aCairo : _bHeba Ibrahem Mahmoud Moftah , _c2015 |
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300 |
_a143 P. : _bfacsimiles ; _c25cm |
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502 | _aThesis (M.Sc.) - Cairo University - Faculty of Medicine- Department of Dermatology and Venerology | ||
520 | _aBackground:Psoriasis is a common chronic systemic inflammatory disease associated with abnormal lipid metabolism, andincreased prevalence of atherosclerosis. Ultraviolet (UV) phototherapy is a well-established therapeutic line for psoriasis. Oxidized LDL (ox-LDL) results from photo-induced oxidative stress. High sensitive C- reactive protein (hs-CRP) isa biomarker of cardiovascular (CVS) risk in addition to other imaging techniques. Objectives: To assess the effect of Psoralen and UV-A (PUVA) on cardiometabolic profile of patients with psoriasis with and without atherosclerosis. Methods:A comparative clinical trial was performed for 17 months, 91patients with chronic plaque psoriasis were examined. Fifty patients fulfilled the criteria for inclusion. Fifteen apparently normal individualswere included as controls.Twenty seven adult patients with psoriasis were put in one of the two arms of the study: with atherosclerosis (high risk) and without atherosclerosis (low risk). Duplex ultrasonography, body mass index (BMI), waist circumference, arterial blood pressure (ABP),high sensitive C reactive protein (hs-CRP), oxidized LDL(ox-LDL), lipid profile and fasting blood sugar (FBS) were assessed before and after 36 sessions of PUVA. Data analysis in the comparative clinical trial included total group analysis and subgroup analysis. Correlations were performed | ||
530 | _aIssued also as CD | ||
653 | 4 | _aComparative clinical trial | |
653 | 4 | _aPsoriasis | |
653 | 4 | _aPUVA | |
700 | 0 |
_aSahar Abdelatty , _eSupervisor |
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700 | 0 |
_aVanessa Galal Hafez , _eSupervisor |
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700 | 0 |
_aWedad Zoheir Mostafa , _eSupervisor |
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856 | _uhttp://172.23.153.220/th.pdf | ||
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_aAml _eCataloger |
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905 |
_aNazla _eRevisor |
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_2ddc _cTH |
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_c55892 _d55892 |