| 000 | 03121cam a2200349 a 4500 | ||
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| 003 | EG-GiCUC | ||
| 005 | 20250223031452.0 | ||
| 008 | 160410s2015 ua dh f m 000 0 eng d | ||
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_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.08.07.M.Sc.2015.Ne.P | ||
| 100 | 0 | _aNehal Sameh Mohammed Ramadan | |
| 245 | 1 | 0 |
_aPhytochemical and Biological Investigation of Justicia spicigera Family Acanthaceae / _cNehal Sameh Mohammed Ramadan ; Supervised Mostafa Aly Abdelkawy , Nagwa Elsayed A. Awad , Enas Hussein Abdelrahman |
| 246 | 1 | 5 | _aدراسة فيتوكيميائية وبيولوجية لنبات الجاستيسيا سبيسحيرا - العائلة الاكانثية |
| 260 |
_aCairo : _bNehal Sameh Mohammed Ramadan , _c2015 |
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| 300 |
_a192 P. : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacognosy | ||
| 520 | _aThe presented thesis aimed at the discovery of the therapeutic agents derived from Justicia spicigera (Family: Acanthaceae) which can be useful in drug industry. The total saponin content gave concentration of 0.2083582 mg/ g of the dried powder as standard diosgenin. GLC analysis of the cold & hot mucilage hydrolyzate revealed the presence of seven free sugars including , Arabinose, ribose, rhamnose,sorbitol, galactose and glucose. The total phenolic content (TPC) was determined in all the extracts and fractions as gallic acid equivalents (GAE) to give results of 9.13±0.32, 13.63±0.51, 42.94±0.62, 8.76±0.73, 42.39±0.14 expressed as mg/g for petroleum ether fraction, chloroformic fraction, ethyl acetate fraction, butanol fraction, and water extract respectively. Analysis of total amino acids content yielded 0.3% ,16 amino acids were identified, the main of which are, Glutamic acid(40.87 %) , Aspartic acid( 8.35 %), Arginine (7.53 %), phenylalanine (6.23 %), leucine (5.85 % ). The yield of the volatiles is 0.02%. 1-Octen-3-ol, Hexenal 2E , Decenal 2E, are the major constituents of the volatile content of the plant of percentages (62.52%, 10.66%, 9.29%), respectively. GC/MS analysis of the unsaponifiable matters revealed the identification of sixteen compounds, amounting 94.67 %. Identified saponifiable matters represented 53.95 %. Six main compounds assigned as P1-P6 were isolated from the pet ether fraction and turned out to be hentriacontane, tritriacontane, octacosanol, triacontanol, phytol & Ý-sitosterol. The use of HPLC led to the identification of delphinidin chloride in anthocyanin extract and ethyl acetate fraction which recorded a concentration of 12.075 and 2.149 mg/100g, respectively | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aAcanthaceae | |
| 653 | 4 | _aAnthocynins | |
| 653 | 4 | _aJusticia spicigera | |
| 700 | 0 |
_aEnas Hussein Abdelrahman , _eSupervisor |
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| 700 | 0 |
_aMostafa Aly Abdelkawy , _eSupervisor |
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| 700 | 0 |
_aNagwa Elsayed A. Awad , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
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_aAml _eCataloger |
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_aNazla _eRevisor |
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| 942 |
_2ddc _cTH |
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| 999 |
_c55937 _d55937 |
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