000			03161cam a2200349 a 4500
003			EG-GiCUC
005			20250223031453.0
008			160411s2015 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.11.31.Ph.D.2015.Am.R
100	0		_aAmr Othman Othman
245	1	4	_aThe role of pet/ct in the initial staging and evaluation of therapeutic response in assessment of extranodal non hodgkin lymphoma / _cAmr Othman Othman ; Supervised Manar Hussein Abdelsattar , Ahmed Mohamed Wafaie , Sherief Mohamed Elrefaei
246	1	5	_aدور الاشعة المقطعية بالأنبعاث البوزيترونى فى التدريج الأولى و لتقييم الاستجابه العلاجيه في تأثر ما دون العقد الليمفاويه لأورام الغير هودجكين الليمفاويه
260			_aCairo : _bAmr Othman Othman , _c2015
300			_a146 Leaves : _bsharts , facsimiles ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis
520			_aThe aim of this work was to evaluate the role the PET/CT in initial diagnosis and staging of lymphoma, assessment of response to radio or chemotherapy therapy, follow up and assessment of remissions and relapses in patients with lymphoma, detection of recurrence, Highlighting the advantages obtained by using the two modalities together through a combined PET/CT in-line system than the advantage gained by using each modality alone. In particular, a five-point scale (Deauville criteria) to grade response using PET-CT, which can be adapted to suit requirements for early- and late- therapeutic response assessment. Results: Lymphoma is the most common primary hematopoietic malignancy. The extra nodal involvements in NHL are compromising in approximately 40% of patients. PET/CT mostly upstaged disease when compared with CT alone. The overall comparison between CECT and PET/CT in groups of our study showed significant sensitivity of PET/CT in LN, splenic, bone marrow and other extranodal affection and it showed relative moderate specificity in other extranodal detection. Lymph nodes detection on PET-CT images showed high sensitivity of 100% with low specificity (25%) and significant P value 0.0001 and fair agreement (Kappa 0.222). PET CT also had sensitivity of about 90.9% and specificity of about 82.1% in detection of splenic involvement in NHL and significant P value 0.001 and substantial agreement (Kappa 0.610). It had high sensitivity (100%) and specificity (74.5%) for the evaluation of extra nodal involvement than contrast enhanced CT and fair agreement (Kappa 0.610)
530			_aIssued also as CD
653		4	_aDeauville criteria
653		4	_aLymphoma
653		4	_aPET/CT
700	0		_aAhmed Mohamed Wafaie , _eSupervisor
700	0		_aManar Hussein Abdel Sattar , _eSupervisor
700	0		_aSherief Mohamed Elrefaei , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aSoheir _eCataloger
942			_2ddc _cTH
999			_c55955 _d55955