000			02212cam a2200349 a 4500
003			EG-GiCUC
005			20250223031453.0
008			160411s2015 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.11.33.Ph.D.2015.Mo.O
100	0		_aMohamed Yousef Salah
245	1	0	_aObesity-related colorectal carcinoma through insulin resistance, insulin growth factor-1 (IGF-1) And IGF binding protein-3 (IGFBP-3) and their genetic polymorphism / _cMohamed Yousef Salah ; Supervised Ayman Yousry Abdelrahim , Mohammad Salah Abdelbary , Sherif Hamdy
246	1	5	_aالعلاقة ما بين السمنة وأورام القولون السرطانية من خلال مقاومة الأنسولين و معامل نمو الأنسولين رقم {u٠٦ئ١} والبروتين الرابط رقم {u٠٦ئ٣} و الاختلال الجيني لهم
260			_aCairo : _bMohamed Yousef Salah , _c2015
300			_a104 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine
520			_aIn Egypt, CRC represents about 4% of total cancers in both sexes. Variation in environmental risk factors particularly the higher content of dietary fibers, more physical activity and lower obesity rates can explain for the different incidence rates between Egypt and the western countries . The increased IGF-I bioavailability may, over time, increase the risk of colorectal cancer. This new evidence for biologic interactions among insulin, IGF-I, and IGFBPs in the context of colorectal carcinogenesis provides a potential mechanism through which diet and associated factors may increase the risk of this cancer
530			_aIssued also as CD
653		4	_aBinding Protein-3
653		4	_aColorectal Carcinoma
653		4	_aIGF-1
700	0		_aAyman Yousry Abdelrahim , _eSupervisor
700	0		_aMohammad Salah Abdelbary , _eSupervisor
700	0		_aSherif Hamdy , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aSoheire _eCataloger
942			_2ddc _cTH
999			_c55959 _d55959