000			03475cam a2200349 a 4500
003			EG-GiCUC
005			20250223031458.0
008			160423s2015 ua h f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.11.04.Ph.D.2015.Ra.A
100	0		_aRaafat Hassan Mohamed Saleh
245	1	0	_aAssessment of left ventricular mechanical dyssynchrony in patients with severe mitral regurgitation of rheumatic etiology / _cRaafat Hassan Mohamed Saleh ; Supervised Soliman Ghareeb , Wafaa Elaroussy , Azza Farrag
246	1	5	_aتقييم الاختلال التزامني الميكانيكي للبطين الايسر في مرضي الصمام الميترالي ذو الارتجاع الشديد نتيجة الحمي الروماتيزمية
260			_aCairo : _bRaafat Hassan Mohamed Saleh , _c2015
300			_a159 P. : _bfacsimiles ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Cardiology
520			_aThe degree of left ventricular mechanical dyssynchrony in patients with severe mitral regurgitation of rheumatic etiology is not well known. Echocardiographic methods have been used to assess LV mechanical dyssynchrony, are still lagging. Results: There was statistically significant difference between the two groups regarding Ts-SD, Ts-Dif, corrected Ts-SD and corrected Ts-Dif (p = 0.000). There was statistically significant differences between the two groups regarding Tmsv16-SD% and Tmsv12-SD% (p = .026 p = 0.027) respectively, and also there was statistically significant difference between the two groups regarding Tmsv6- SD% (p = 0.017).and Tmsv6 -Dif% ( p = 0.016) . In our study the prevelance of LV dyssynchrony was [(22.5{u066A})(7 RHD patients from 31 RHD patients)] by using SDI cut-off 8.3% , and the prevelance of LV dyssynchrony was [ (19.4{u066A}) (6 RHD patients from 31 RHD patients)] by using the Yu index cut-off {u02C3}32.6 ms. Pearson's correlation coefficient in RHD patients showed Dyssynchrony parameters: Tmsv16-SD% and Tmsv12-SD% were statistically significant negatively correlated with 2DEF ( r = - 0. 535 P = 0.002) ( r = -5.489 P = 0.042 ) and with 3DEF ( r = - 5.518 p = 0.020) ( r =-0.255 P = 0.04) respectively., but Tmsv16-SD% was Positive statistically significant correlated with LVESD (r = 0.471 P = 0.007) with LVESV( r = 0.990 p = 0.000 ) with EDV3D (r = 0.527 P = 0.002) and with ESV3D ( r = 0.551 p=0.002). Tmsv12 {u2013}SD% was positive statistically significant correlated with EDV3D ( r = 0.502 P= 0.004 ) and with ESV3D ( r = 0.478 P = 0.002) with PASP ( r = 0.356 P= 0.030 ) with regugitant volume ( r = 0.420 P = 0.013) . 2DEF was Positive statistically significant correlated with 3DEF (r = 0.409 P = 0.022). Conclusion: this is the first study to demonstrate that in patients with severe MR due to rheumatic etiology there is left ventricular dyssynchrony. RT3DE and TDl were able to objectively and accurately evaluate LV function and LV dyssynchrony
530			_aIssued also as CD
653		4	_aDyssynchrony
653		4	_aMitral Regurgitation
653		4	_aRheumatic
700	0		_aAzza Farrag , _eSupervisor
700	0		_aSoliman Ghareeb , _eSupervisor
700	0		_aWafaa Elaroussy , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aSoheir _eCataloger
942			_2ddc _cTH
999			_c56150 _d56150