000			03319cam a2200349 a 4500
003			EG-GiCUC
005			20250223031503.0
008			160507s2015 ua d f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.10.19.Ph.D.2015.Em.L
100	0		_aEman Mohamed Ismail Hassan
245	1	0	_aLaboratory and field and studies for evaluation of disinfectants and chemicals used in different fish farms / _cEman Mohamed Ismail Hassan ; Supervised Mamdouh Mostafa Hamoud , Hussein Abdelhay Kaoud , Nermeen M. M. Moustafa
246	1	5	_aدراسات حقلية ومعملية لتقييم المطهرات و المركبات الكيميائية المستخدمة في المزارع السمكية المختلفة
260			_aCairo : _bEman Mohamed Ismail Hassan , _c2015
300			_a169 P. : _bcharts ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Veterinary Hygiene and Management
520			_aA key element of disinfection is the choice of a suitable disinfecting agent in appropriate concentration for sufficient contact time. The presented study aimed to investigate the bactericidal effectiveness of six commercial disinfectants against seven prevalent and common bacterial genera causing disease problems in aquatic ecosystem mostly were gram negative rods. The evaluation assays was conducted in two stages of experimental work; in vitro laboratory testing following Quantitative European suspension BS CEN 1276 test methods and requirements, followed by in vivo evaluation of bactericidal effectiveness of the tested disinfectants after acute and chronic toxicity testing following OECD (guideline no. 203) test method; for determination of Median Lethal concentration (LC50) and No Observed Effect Concentration (NOEC), beside investigation the safety application of the tested disinfectants into aquatic systems. With exception of Biosentry® Iodine{u2122}, nearly all tested disinfectants at 1.25 the recommended use dilution and after 5 min contact time achieved significant log reduction (P {u02C2} 0.05) and pass criteria of at least 5 against the majority of tested organisms, except Vibrio alginolyticus that was noticed to be resistant to most tested disinfectants. The in vivo work revealed that efficient bactericidal effectiveness was achieved by Virkon-S®, Aldekol des- Gda® and Peraclean® at NOEC against three selected strains, Aeromonas hydrophila (gyr-B LC012344), Pseudomonas aeruginosa and V. alginolyticus at ID50 inspite of their concentrations were lower than the LC50 values, on the other hand TH4® disinfectant failed to achieve the bactericidal effect against the 3 inoculated strains at their ID50, inspite of its efficient bactericidal reduction efficacy under in vitro conditions
530			_aIssued also as CD
653		4	_aCEN 1276 test
653		4	_aDisinfectants
653		4	_aIn vitro/ in vivo Evaluation
700	0		_aHussein Abdelhay Kaoud , _eSupervisor
700	0		_aMamdouh Mostafa Hamoud , _eSupervisor
700	0		_aNermeen Moustafa Mohamed Moustafa , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aSoheir _eCataloger
942			_2ddc _cTH
999			_c56299 _d56299