000			03117cam a2200349 a 4500
003			EG-GiCUC
005			20250223031505.0
008			160510s2015 ua d f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.32.M.Sc.2015.Ay.H
100	0		_aAyman Eid Girgis
245	1	0	_aHealth related quality of life in rheumatoid arthritis patients : _bCorrelation with disease activity, disability index and radiological damage / _cAyman Eid Girgis ; Supervised Ola Mohammed Ragab , Hania Salah Zayed , Enas Abolkheir Abdelaleem
246	1	5	_aنوعية الحياة المتعلقة بالصحة لمرضى الروماتويد وعلاقتها بنشاط المرض ومؤشر العجز وتآكل المفاصل في الأشعة
260			_aCairo : _bAyman Eid Girgis , _c2015
300			_a198 P. : _bcharts ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Rheumatology and Rehabilitation
520			_aObjective: to evaluate Health Related Quality of Life (HRQoL) in Rheumatoid Arthritis (RA) patients, evaluate the effect of early treatment with Disease Modifying Anti-Rheumatic Drugs (DMARDs) on HRQoL and evaluate the effect of treatment adherence and factors affecting it. Results: RA patients had a significantly lower Physical Component Summary (PCS) score than healthy controls (P=0.001). Group A patients had significantly Lower disease activity (P = 0.001), lower MHAQ score (P = 0.001), less x-ray erosions (P = 0.001) and significantly higher PCS (P = 0.001) and Mental Component Summary (MCS) (P = 0.003) scores than group B patients. Adherent patients had significantly less disease activity (P<0.001), less joint destruction in X-ray (P=0.02) and lower MHAQ score (P<0.001) than non-adherent patients. Also PCS and MCS scores were significantly higher in adherent patients (P = 0.001 and 0.042 respectively). Factors that were associated with lower adherence rate were: younger age (P = 0.008), rural residence (P = 0.045), lack of patients{u2019} awareness about their condition (P = 0.001), fear from medication side effects (P = 0.006), lack of belief in medication effectiveness (P = 0.001), occurrence of medication side effects (P = 0.027), absence of medical insurance (P = 0.049) and difficult ambulation (P = 0.039). Conclusion: RA can enormously affect HRQoL. Early diagnosis and treatment by a rheumatologist within the first 6 months of disease onset together with adherence to DMARDs appear to significantly improve outcome and quality of life in RA patients.
530			_aIssued also as CD
653		4	_aDisease modifying Anti-Rheumatic drugs
653		4	_aHealth Related Quality of Life
653		4	_aRheumatoid Arthritis
700	0		_aEnas Abolkheir Abdelaleem , _eSupervisor
700	0		_aHania Salah Zayed , _eSupervisor
700	0		_aOla Mohammed Ragab , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aSoheir _eCataloger
942			_2ddc _cTH
999			_c56380 _d56380