000 | 02484cam a2200349 a 4500 | ||
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003 | EG-GiCUC | ||
005 | 20250223031534.0 | ||
008 | 161004s2015 ua d f m 000 0 eng d | ||
040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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041 | 0 | _aeng | |
049 | _aDeposite | ||
097 | _aPh.D | ||
099 | _aCai01.11.01.Ph.D.2015.Di.I | ||
100 | 0 | _aDina Atteya Mohamed Atteya | |
245 | 1 | 0 |
_aImpact of augmented renal clearnce on enoxaparin therapy in critically ill pateints / _cDina Atteya Mohamed Atteya ; Supervised Hala Ezzat Mohamed Abdelnaeem , Mona Hossam Eldin Abdelhameed , Ahmed Mohamed Ibrahim Hasanin |
246 | 1 | 5 | _aتأثير زيادة التنقية الكلوية على علاج بالإينوكسبارين في مرضى الحالات الحرجة |
260 |
_aCairo : _bDina Atteya Mohamed Atteya , _c2015 |
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300 |
_a58 P. : _bcharts ; _c25cm |
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502 | _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anaesthesia | ||
520 | _aFifty critically ill patients receiving enoxaparin prophylactic dose (40mg/day) were included in the study. Creatinine clearance was measured and patients were divided into two groups: normal kidney function group (group C) and augmented renal clearance group (group A). serum anti-factor Xa was measured at baseline, four hours, 12 hours, and 24 hours. Both groups were compared regarding demographic data, severity scores, kidney function, and anti-factor Xa activity.Results Twenty patients (40%) showed ARC and thirty patients (60%) showed normal kidney function. Creatinine clearance was 214±6 in group A versus 112±11 in group C (P=0.001). Serum anti-factor Xa levels was similar in the two groups after four hours (0.2±0.07 Vs 0.2±0.05, P=1). Serum anti-Xa levels were significantly lower in group A compared to group C at 12 and 24 hours (0.06±0.03 Vs 0.1±0.04, P=0.004), (0.01±0.01 Vs 0.05±0.01, P=0.001) respectively.Conclusion ARC patients showed short activity of enoxaparin. This finding draws the attention towards dose adjustment in this type of patients | ||
530 | _aIssued also as CD | ||
653 | 4 | _aAnaesthesia | |
653 | 4 | _aCritically ill | |
653 | 4 | _aEnoxaparin therapy | |
700 | 0 |
_aAhmed Mohamed Ibrahim Hasanin , _eSupervisor |
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700 | 0 |
_aHala Ezzat Mohamed Abdelnaeem , _eSupervisor |
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700 | 0 |
_aMona Hossam Eldin Abdelhameed , _eSupervisor |
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856 | _uhttp://172.23.153.220/th.pdf | ||
905 |
_aEnas _eCataloger |
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905 |
_aNazla _eRevisor |
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942 |
_2ddc _cTH |
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999 |
_c57340 _d57340 |