000 02810cam a2200349 a 4500
003 EG-GiCUC
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008 160824s2016 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.16.Ph.D.2016.Ha.H
100 0 _aHanan Abdalla Hassan Bastawy
245 1 0 _aHistological study on the possible protective effect of thyroid hormone on hepatic ischemia reperfusion injury in male rats /
_cHanan Abdalla Hassan Bastawy ; Supervised Mohammed Ahmed Abdalhafez , Mira Farouk Youssef , Dalia Ibrahim Ismail
246 1 5 _aدراسة هستولوجية وهستوكيميائية مناعية على التأثيرالوقائي المحتمل لهرمون الغدة الدرقية في الأصابة التى يسببها إنقطاع الدم ثم إعادة ضخه فى كبد الجرذان
260 _aCairo :
_bHanan Abdalla Hassan Bastawy ,
_c2016
300 _a121 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Histology
520 _aThis study aimed at evaluating the effects of thyroid hormone (TH) on Ischemia reperfusion injury (IRI) in rat liver. Results: group II, showed no significant difference in the mean serum AST & ALT levels compared to the control rats. H&E sections revealed similar histological architecture of the liver parynchema as in control group. The statistical difference of the optical density of PAS and the mean area % of CD68 & iNOS immunoreactivity was non significant as compared with the control.. Group III showed significant increased in the mean serum AST & ALT levels compared to the control group. The H&E stained liver sections revealed disorganization, degeneration and necrosis of the hepatocytes with significant decrease in of the optical density of PAS and significant increase in the mean area % of CD68 & iNOS immunoreactivity compared to the control. Group VI showed significant decrease in the mean serum AST & ALT levels with decrease in the histological alterations caused by IRI. There was significance increase in the optical density of PAS reaction and significance decrease in the mean area % of CD68 and iNOS immunoreactivity when compared to the IRI group. Conclusion: TH have protective effect against hepatic IRI
530 _aIssued also as CD
653 4 _aCD68
653 4 _aIschemia reperfusion injury
653 4 _aThyroid hormone
700 0 _aDalia Ibrahim Ismail ,
_eSupervisor
700 0 _aMira Farouk Youssef ,
_eSupervisor
700 0 _aMohammed Ahmed Abdalhafez ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSoheir
_eCataloger
942 _2ddc
_cTH
999 _c57538
_d57538