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008 | 160827s2016 ua dh f m 000 0 eng d | ||
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_aEG-GiCUC _beng _cEG-GiCUC |
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041 | 0 | _aeng | |
049 | _aDeposite | ||
097 | _aPh.D | ||
099 | _aCai01.08.03.Ph.D.2016.Ba.A | ||
100 | 0 | _aBasma Mohamed Abdelhameed Eltanany | |
245 | 1 | 0 |
_aAnalysis of some multicomponent preparations used for treatment of mucous membranes disorders / _cBasma Mohamed Abdelhameed Eltanany ; Supervised Fatma Issa Khattab , Maha Abdelmonem Hegazy , Medhat Ahmed Alghobashy |
246 | 1 | 5 | _aتحليل بعض المستحضرات متعددة المحتوى المستخدمة لعلاج الأغشية المخاطية |
260 |
_aCairo : _bBasma Mohamed Abdelhameed Eltanany , _c2016 |
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300 |
_a272 P. : _bcharts , facsimiles ; _c25cm |
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502 | _aThesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry | ||
520 | _aMucous membranes including vaginal, nasal and mouth membranes are vulnerable to different disorders such as inflammation, congestion, fungal and/or bacterial infections. For sufficient treatment of these disorders, local and/or systemic multicomponent pharmaceutical preparations are used. Nasal preparations include ingredients such as antihistamines, alpha agonists, anti- inflammatory and others. The active ingredients cover a range of structures with widely varying polarities and include both acidic and basic compounds. Phenylephrine, Dimetindene Maleate, Carbinoxamine Maleate, Sodium Cromoglycate and Oxymetazoline Hydrochloride are widely used in combinations for the clinical treatment of common cold, sinusitis, bronchitis and respiratory allergies. The aim of this work was to develop potential, reliable fast and efficient analytical methodologies for various dosage forms which can estimate all the major ingredients of multicomponent formulations used for treatment of mucous membranes disorders. Also to investigate purity using analytical methods which are capable of determining the studied drugs in their combinations and in presence of their impurities. Various analytical techniques were used for the simultaneous analysis of these mixtures. The proposed methods were simple, accurate, and reproducible, which would be feasible, and sensitive for the determination of the studied drugs. The proposed methods were validated according to ICH-guidelines | ||
530 | _aIssued also as CD | ||
653 | 4 | _aDimetindence Maleate | |
653 | 4 | _aMucous memberanes disorders | |
653 | 4 | _aPhenylephrine | |
700 | 0 |
_aFatma Issa Khattab , _eSupervisor |
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700 | 0 |
_aMaha Abdel Monem Hegazy , _eSupervisor |
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700 | 0 |
_aMedhat Ahmed Alghobashy , _eSupervisor |
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856 | _uhttp://172.23.153.220/th.pdf | ||
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_aNazla _eRevisor |
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905 |
_aSamah _eCataloger |
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_2ddc _cTH |
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